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Cobra genome may yield new antivenoms, venom-based drugs

January 6, 2020

A reference genome from the Indian cobra compiled in an international collaborative study should lead to the development of new safer and more effective antivenoms, while the elucidated genome and predicted associated proteome may be a powerful platform for studies of venomous snakes.

BioWorld MedTech’s Neurology Extra for Jan. 3, 2020

January 3, 2020

By Andrea Applegate

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Keeping you up to date on recent developments in neurology.

Another role for HIF-2a

Glutamine transporter variant identified as new cancer target

January 3, 2020

By John Fox

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A mitochondrial glutamine transporter variant is a key regulator of glutamine metabolism and metabolic reprogramming in cancer cells, and targeting such transporters could be a new strategy for controlling tumor growth, Korean researchers reported online in the Dec. 19, 2019, edition of Cell Metabolism.

Bench Press for Jan. 3, 2020

January 3, 2020

By Anette Breindl

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Researchers at the University of Pittsburgh have discovered that intravenous (I.V.) delivery of the Bacille Calmette-Guérin (BCG) vaccine sharply improved its ability to provoke a protective T-cell response in the lungs.

Innate immune system set to join antitumor fray

January 2, 2020

By Anette Breindl

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The natural immune system has two lines of defense that complement each other. In response to an infection, a rapid but fairly unspecific and short-lived response by the innate immune system is followed by the precisely targeted attack of the B and T cells of the adaptive immune system, followed by immune memory that can last a lifetime

BioWorld MedTech’s Diagnostics Extra for Jan. 2, 2020

January 2, 2020

By Meg Bryant

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Keeping you up to date on recent developments in diagnostics.

Snow White and the Seven snow white genomes

Lack of genomic diversity means actionable mutations are left undiscovered

December 31, 2019

By Anette Breindl

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Genome sequencing is enabling new insights into the genetic aspects of health and disease that have touched just about every aspect in biomedicine. It is also, like the “skin”-colored crayons of yore, disproportionately focused on the Caucasian segment of the population. And that is a loss for everyone.

Snow White and the seven snow white genomes

Lack of genomic diversity means actionable mutations are left undiscovered

December 31, 2019

By Anette Breindl

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BioWorld MedTech’s Oncology Extra for Dec. 31, 2019

December 31, 2019

By Mark McCarty

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Keeping you up to date on recent developments in oncology.

Year in Review: Promise of genomics finally impacting clinical care

December 30, 2019

By Nuala Moran

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LONDON – Twenty years on from sequencing of the first draft of the human genome and the associated hype, 2019 was the year that the science of genomics truly began to make an impact in health care.

Researchers develop artificial kidney capable of purifying blood to create its own ‘urine’
BioWorld MedTech
Roseville, Calif.-based US Kidney Research Corp., formerly Curion Research Corp., has been working on its waterless renal replacement technology since its...
Micro-cap Pavmed takes on Medtronic, Exact with first DNA-based Barrett’s esophagus test
BioWorld MedTech
The screening of at-risk patients for Barrett’s esophagus, a precursor to esophageal cancer, has long been a goal for health systems. Currently, most patients...
Year in Review: From capital markets to CRISPR, 2019 a pretty good year for biopharma
BioWorld
For biopharma, 2019 can be described as a terrific year – with a few asterisks. The financial markets were flourishing, with venture capital dollars, in...
Empirico scores $660M deal with Ionis and lands a series A-2 fundraiser
Deals and M&A
Nurix eligible for $2.5B in milestone payments in Sanofi deal
BioWorld
Nurix Therapeutics Inc. landed its second big pharma collaboration in seven months when it signed with Sanofi SA to discover, develop and commercialize a pipeline...

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