Keeping you up to date on recent developments in diagnostics, including: Imaging methods reveal underlying cause of unexplained heart attack; Questionnaire predicts people at high risk for heart disease; Bias skews tally on imaging diagnostic test accuracy studies.
A study by Australian microbiologists at Queensland, Melbourne and Griffiths universities has shown that the candidate neurodegenerative disease drug PBT-2, combined with a polymyxin antibiotic, induced potent antimicrobial activity against polymyxin-resistant gram-negative pathogens.
Keeping you up to date on recent developments in orthopedics, including: Exoskeleton-assisted walking improves mobility in individuals with spinal cord injury; Skoltech scientists developed a novel bone implant manufacturing method; Novel technique 'stuns' arthritis pain in shoulder and hip; New research reveals potential treatment to delay and manage osteoarthritis.
Keeping you up to date on recent developments in oncology, including: Prolonged androgen-deprivation therapy confirmed as hit on CV health; Nanoparticle fights pancreatic cancer’s chemo resistance; Linking two liver cancer culprits; Reversal of pumping direction is reversal of fortune for tumor cells; Active surveillance backed for Black men with prostate cancer.
Researchers at the University of California at San Francisco have developed a method to diagnose any known pathogen from any body fluid within a day – or, depending on the sequencing method, within a few hours. For an unknown pathogen, the method spits out its nearest known relative.
BioWorld looks at translational medicine, including: Reversal of pumping direction is reversal of fortune for tumor cells; Cholesterol drug affects checkpoint blockade via MHC1; Heart development protein has role in adult immunity.
Chinese scientists have been the first to show that combining anti-cancer poly [ADP-ribose] polymerase (PARP) inhibitors with radiotherapy may be effective for treating ependymoma CNS tumors expressing elevated levels of the protein chromosome X open reading frame 67 (CXorf67).
Most of a pancreatic tumor is not made up of tumor cells – a double-edged sword for the tumor cells. This connective tissue component impedes blood flow, which is part of what makes pancreatic cancer so drug-resistant. But the lack of blood also means a lack of oxygen and nutrients, so pancreatic tumors must find alternate ways to feed themselves. That’s where nerves come in. In the Nov. 2, 2020, online issue of Cell, researchers published new insights into how innervation feeds tumors, and how to stop them from doing so.
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