BioWorld looks at translational medicine, including: Reversal of pumping direction is reversal of fortune for tumor cells; Cholesterol drug affects checkpoint blockade via MHC1; Heart development protein has role in adult immunity.
Chinese scientists have been the first to show that combining anti-cancer poly [ADP-ribose] polymerase (PARP) inhibitors with radiotherapy may be effective for treating ependymoma CNS tumors expressing elevated levels of the protein chromosome X open reading frame 67 (CXorf67).
Most of a pancreatic tumor is not made up of tumor cells – a double-edged sword for the tumor cells. This connective tissue component impedes blood flow, which is part of what makes pancreatic cancer so drug-resistant. But the lack of blood also means a lack of oxygen and nutrients, so pancreatic tumors must find alternate ways to feed themselves. That’s where nerves come in. In the Nov. 2, 2020, online issue of Cell, researchers published new insights into how innervation feeds tumors, and how to stop them from doing so.
Keeping you up to date on recent developments in cardiology, including: New cardiac arrest resuscitation treatment demonstrated 100% success rate in cannulation; How additional heart imaging can help certain women; Heart development protein has role in adult immunity.
A Polish/Dutch team of investigators has reported new insights into the structure of the SARS-CoV-2 genome that suggests it could be amenable to both small-molecule and oligonucleotide drugs.
Keeping you up to date on recent developments in neurology, including: Individualized brain stimulation therapy improves aphasia in stroke survivors; Weekly physical activity may help prevent Alzheimer’s in people with mild cognitive impairment; Diagnosing Parkinson’s via mitochondria interaction networks.
Keeping you up to date on recent developments in diagnostics, including: Predicting schizophrenia; Functional analysis complements sequencing; Early screening for cognitive decline; Rapid test highly accurate for PJI infections.
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