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Glutamine transporter variant identified as new cancer target

Jan. 7, 2020
By John Fox
A mitochondrial glutamine transporter variant of the SLC1A5 gene is a key regulator of glutamine metabolism and metabolic reprogramming in cancer cells, and targeting such transporters could be a new strategy for controlling tumor growth, Korean researchers reported online in the Dec. 19, 2019, edition of Cell Metabolism.
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BioWorld MedTech’s Oncology Extra for Jan. 7, 2020

Jan. 7, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology.
Read More

BioWorld MedTech’s Cardiology Extra for Jan. 6, 2020

Jan. 6, 2020
By Liz Hollis
Keeping you up to date on recent developments in cardiology.
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Indian cobra
Pick your poison

Cobra genome may yield new antivenoms, venom-based drugs

Jan. 6, 2020
By John Fox
A reference genome from the Indian cobra compiled in an international collaborative study should lead to the development of new safer and more effective antivenoms, while the elucidated genome and predicted associated proteome may be a powerful platform for studies of venomous snakes.  
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BioWorld MedTech’s Neurology Extra for Jan. 3, 2020

Jan. 3, 2020
By Andrea Applegate
Keeping you up to date on recent developments in neurology.
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Glutamine skeletal formula
Another role for HIF-2a

Glutamine transporter variant identified as new cancer target

Jan. 3, 2020
By John Fox
A mitochondrial glutamine transporter variant is a key regulator of glutamine metabolism and metabolic reprogramming in cancer cells, and targeting such transporters could be a new strategy for controlling tumor growth, Korean researchers reported online in the Dec. 19, 2019, edition of Cell Metabolism.  
Read More

Bench Press for Jan. 3, 2020

Jan. 3, 2020
By Anette Breindl
Researchers at the University of Pittsburgh have discovered that intravenous (I.V.) delivery of the Bacille Calmette-Guérin (BCG) vaccine sharply improved its ability to provoke a protective T-cell response in the lungs.
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NK cell destroying a cancer cell

Innate immune system set to join antitumor fray

Jan. 2, 2020
By Anette Breindl
The natural immune system has two lines of defense that complement each other. In response to an infection, a rapid but fairly unspecific and short-lived response by the innate immune system is followed by the precisely targeted attack of the B and T cells of the adaptive immune system, followed by immune memory that can last a lifetime
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BioWorld MedTech’s Diagnostics Extra for Jan. 2, 2020

Jan. 2, 2020
By Meg Bryant
Keeping you up to date on recent developments in diagnostics.
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Illustration of children with different skin tones
Snow White and the Seven snow white genomes

Lack of genomic diversity means actionable mutations are left undiscovered

Dec. 31, 2019
By Anette Breindl
Genome sequencing is enabling new insights into the genetic aspects of health and disease that have touched just about every aspect in biomedicine. It is also, like the “skin”-colored crayons of yore, disproportionately focused on the Caucasian segment of the population. And that is a loss for everyone.
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