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BioWorld MedTech’s Cardiology Extra for April 5, 2021

April 5, 2021
By Mark McCarty
Keeping you up to date on recent developments in cardiology, including: Space flight, swimming both hard on LV mass; Workaholism a bad deal for coronary artery disease patients; New approach to stem cell therapy effective in animal models of HF.
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BioWorld MedTech’s Neurology Extra for April 2, 2021

April 2, 2021
By Andrea Applegate and Anette Breindl
Keeping you up to date on recent developments in neurology, including: DBS shows promise in treating OCD patients with comorbidities; COVID-19-associated seizures linked to higher risk of death; Antibodies could make things worse in neurodegeneration; Ultrarare variants give insights into schizophrenia.
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BioWorld MedTech’s Diagnostics Extra for April 1, 2021

April 1, 2021
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Blood-based test may help detect early Alzheimer’s disease; AI-based tool helps predict course of COVID-19; Myeloid cells differ in primary and recurrent glioblastoma.
Read More
T cells
Bench Press

Breaks are good for T-cell productivity, too

April 1, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Premetastatic niche is prepared via leaky gut in colorectal cancer; Brain metastases of breast cancer depend on fatty acid synthesis.
Read More
Brain and DNA

Tsukushi protein mutations can lead to hydrocephalus

April 1, 2021
By Anette Breindl
Researchers at Kumamoto University have identified mutations in the proteoglycan Tsukushi as a cause of hydrocephalus. The study, which was published in the March 31, 2021, issue of Science Translational Medicine, adds to the evidence that a significant proportion of hydrocephalus are due to genetic alterations.
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BioWorld MedTech’s Orthopedics Extra for March 31, 2021

March 31, 2021
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Scientists use nanotechnology to detect bone-healing stem cells; Premia reports FDA breakthrough device designation for Its Tops system; 'Break a leg' not so lucky when it leads to limb deformities.
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Brain-DNA illustration

New model of MECP2 duplication syndrome may advance antisense oligonucleotide treatment

March 31, 2021
The neurodevelopmental disorder MECP2 duplication syndrome (MDS) is caused by duplications spanning the methyl-CpG binding protein 2 gene (MECP2) locus, and researchers have shown that the MDS-like phenotype can be reversed in adult symptomatic mice using MECP2-specific antisense oligonucleotides (MECP2-ASOs).
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BioWorld MedTech’s Oncology Extra for March 30, 2021

March 30, 2021
By Mark McCarty
Keeping you up to date on recent developments in oncology, including: NCI team devises method to recruit myeloid cells in pushback against cancer; Algorithm ranks cancer therapies for efficacy; New twist on quantum dots could revolutionize imaging.
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Cancer cell and DNA

Gut microbial metabolites facilitate anticancer therapy

March 30, 2021
By John Fox
A study led by Chinese scientists at Tsinghua University in Beijing has demonstrated that the gut microbial metabolite butyrate can directly modulate the antitumor CD8 "killer" T-cell response and improve chemotherapy efficacy through ID2-dependent IL-12 signaling.
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BioWorld MedTech’s Cardiology Extra for March 29, 2021

March 29, 2021
By Mark McCarty
Keeping you up to date on recent developments in cardiology, including: Algorithms can distinguish varying grades of pulmonary edema in heart failure; Cholesterol-independent heart disease risk gene; Study confirms role of smoking in CAD among Blacks.
Read More
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