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BioWorld - Sunday, December 14, 2025
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Gloved hand holding petri dish in lab

Nullifying necrosis: unfolded protein response inhibitors fight flesh-eating bacteria

Aug. 6, 2021
By Subhasree Nag
Researchers led by Emanuel Hanski at the Hebrew University of Jerusalem have identified a class of molecules that inhibit endoplasmic reticulum (ER) stress and could decrease mortality in mice infected with Streptococcus pyogenes, also known as the group A streptococci.
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Microscope and coronavirus illustration

New study is both reality check and shot in the arm for SARS-CoV-2 drug repurposing

Aug. 5, 2021
By Anette Breindl
Investigators at the University of California at San Francisco have identified a confounder that appears to be behind the purported anti-SARS-CoV-2 effects of a number of therapeutic candidates that were identified via repurposing.
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Doctor and patient consultation

GWAS gives clues to menopause, and healthy aging

Aug. 5, 2021
By Nuala Moran
A genome-wide association study has identified 290 genetic variants, including a wide range of DNA damage response genes, that are associated with age at menopause.
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Microscope and coronavirus illustration

New study is both reality check and shot in the arm for SARS-CoV-2 drug repurposing

Aug. 4, 2021
By Anette Breindl
Investigators at the University of California at San Francisco have identified a confounder that appears to be behind the purported anti-SARS-CoV-2 effects of a number of therapeutic candidates that were identified via repurposing.
Read More
Brain and blood cells

Hong Kong researchers develop blood test for Alzheimer’s disease

Aug. 3, 2021
By Elise Mak
Researchers from The Hong Kong University of Science and Technology (HKUST) have developed a blood test to detect Alzheimer’s disease (AD) early. They said the test has an accuracy level of over 96% and can also monitor disease progression. This is a new approach to detecting AD compared to the commonly used cognitive tests and invasive methods that detect changes in the brain caused by AD.
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Amyloid plaque on nerve cell

In vivo gene editing alleviates amyloid pathologies

Aug. 3, 2021
By John Fox
Brain-wide genome editing via a single systemic dose of modified adeno-associated virus variants that cross the blood-brain barrier may represent a promising new approach for the development of disease-modifying treatments for familial Alzheimer's disease. This strategy could also be applicable to other central nervous system (CNS) disorders, according to a proof-of-concept (PoC) study led by researchers at The Hong Kong University of Science and Technology (HKUST).
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Neurons

Gem gene sparkles as ischemic stroke drug discovery target

Aug. 3, 2021
By John Fox
The collective findings of a new multicenter Japanese study have demonstrated for the first time that expression of the gene Gem via the activity-dependent transcription factor, neuronal PAS domain protein 4 (Npas4), promotes neuroprotection in the injured brain following ischemic stroke.
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Concept illustration of nano-capsules for virus trapping

Virus trap: Early stage nanoshell tech aims to neutralize viruses

Aug. 2, 2021
By Bernard Banga
PARIS – At some point, scientists reported, it may be possible to quarantine viruses rather than humans. For the last two years, European research consortium Virofight has been working on a form of nanotechnology intended to neutralize viruses such as SARS-CoV-2, HIV, influenza and hepatitis viruses.
Read More
Illustration of digital syringe

Evolutionary modeling warns of COVID-19 vaccine resistance

July 30, 2021
By Nuala Moran
LONDON – Relaxing of control measures such as mask wearing and social distancing at a time when most of a population has been vaccinated against COVID-19 greatly increases the probability of the emergence of a vaccine-resistant strain, according to a new modeling study.
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Amyloid plaque on nerve cell

In vivo gene editing alleviates amyloid pathologies

July 30, 2021
By John Fox
Brain-wide genome editing via a single systemic dose of modified adeno-associated virus variants that cross the blood-brain barrier may represent a promising new approach for the development of disease-modifying treatments for familial Alzheimer's disease.
Read More
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