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BioWorld MedTech’s Neurology Extra for April 24, 2020

April 24, 2020
By Andrea Applegate and Anette Breindl
Keeping you up to date on recent developments in neurology, including: Nanocarrier developed for drug delivery across the BBB; 3D face analysis could screen for sleep apnea; Long noncoding RNA has sex-specific role in depression; Noncoding TET2 variants affect neurodegeneration risk.
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Islet clusters

Bench Press for April 24, 2020

April 24, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: Edited stem cells reverse mouse diabetes; Noncoding TET2 variants affect neurodegeneration risk; Pancreatic cancer uses autophagy to hide from immune system; Heart failure hormone has role in sepsis; NRF2 wakes sleeping tumor cells; Oral drug can wake up telomerase; Cheating cell death improves infarct outcomes; Older siblings’ example turns stem cells into heart cells; Lung changes from PD drug hopeful are reversible; Platelets play role in Tylenol toxicity.
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BioWorld MedTech’s Diagnostics Extra for April 23, 2020

April 23, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Automated CT biomarkers predict future CV events; PCR heightens detection of scabies; High BMI linked to dementia via complement component.
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Marburg virus

In antibody ensemble, second fiddles help the neutralizing stars

April 23, 2020
By Anette Breindl
By analyzing the antibody response of a survivor of Marburg virus infection, researchers at the University of Texas Medical Branch and Vanderbilt University Medical Center have gained new insights into the function of non-neutralizing antibodies in fighting infections.
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BioWorld MedTech’s Orthopedics Extra for April 22, 2020

April 22, 2020
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Co-delivery of IL-10 and NT-3 to enhance spinal cord injury repair; Marshall School of Medicine team explores surgery technology resulting in fewer incisions; Researchers discover treatment for spasticity in mice, following spinal cord injuries.
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BioWorld MedTech’s Oncology Extra for April 21, 2020

April 21, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Targeted Interleukin-12 heats up cold tumors; Therapy allows immune system to ‘manganese’ up against cancer; Proton therapy less toxic than IMRT in new study; Technetium supplies struggling under distribution headaches.
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BioWorld MedTech’s Cardiology Extra for April 20, 2020

April 20, 2020
By Liz Hollis and Anette Breindl
Keeping you up to date on recent developments in cardiology, including: Modeling the post-infarct heart; Researchers: Cancer immunotherapy poses threat to heart muscle; Lighting up the path for heart procedures.
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Keith Ligon, chief of neuropathology, Brigham and Women's Hospital

For gliomas, hypermutated does not mean sensitive to checkpoint blockade

April 17, 2020
By Anette Breindl
The largest study to date on hypermutated gliomas has delivered new insights into their origin, as well as their response to several different treatments. Specifically, even though they are hypermutated, such tumors are unlikely to respond to PD-1 blockers.
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BioWorld MedTech’s Neurology Extra for April 17, 2020

April 17, 2020
By Andrea Applegate and Anette Breindl
Keeping you up to date on recent developments in neurology, including: Gene variant may protect against Alzheimer's; Miniature microscope used to study neural circuit activity in nonhuman primate model; Dopamine has epigenetic role in addiction; Depression’s structural problem.
Read More
CRISPR Cas9 illustration

Making neurons from glia alleviates neurodegenerative diseases

April 17, 2020
By John Fox
Chinese scientists have shown for the first time that the down-regulation of a single RNA-binding protein, polypyrimidine tract-binding protein 1 (Ptbp1), locally converted glial cells to neurons and showed promise for treating the symptoms of neurodegenerative diseases in mice.
Read More
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