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Home » Topics » Science » Omics

Omics
Omics RSS Feed RSS

Expected omics results vs. actual omics results
Drug Design, Drug Delivery & Technologies

Incomplete databases can yield false positives in microbiome studies

Feb. 13, 2023
By Subhasree Nag
A study by researchers in Spain suggests that current metagenomic analyses of the microbiome can yield erroneous results, largely due to the incomplete databases that are used to identify microbial DNA sequences. A team led by Clemente Fernández Arias and Federica Bertocchini at the Centro de Investigaciones Biológicas Margarita Salas, Madrid, evaluated current microbiome analysis techniques on computer simulations of microbial communities in a report published on Feb. 8 in PLOS ONE.
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Lungs and bronchiole
Respiratory

Airway microbiome regulates chronic obstructive pulmonary disease

Aug. 30, 2022
By Mar de Miguel
A metabolite derived from the airway microbiome, indole-3-acetic acid (IAA), could become a potential therapeutic candidate for chronic obstructive pulmonary disease (COPD). Researchers at South China Normal University (SCNU) have shown how IAA prevents lung function decline by reducing inflammation, apoptosis and emphysema through IL-22 in the interaction between macrophages and alveolar epithelial cells.
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Dollar sign in lightbulb

Prognomiq lands $46M from Bruker for multiomics platform

March 15, 2022
By Annette Boyle
Prognomiq Inc. nearly doubled its fundraising to date with a new $46 million financing to further develop its multiomics platform to detect cancer and other complex diseases earlier in their development. The financing led by Bruker Corp. along with new investor Catalio Capital Management brought total funds raised $101 million since the company’s founding in 2020.
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Businessman riding unicorn atop arrows in the clouds

Freenome soars into unicorn club with $290M Roche financing

Jan. 11, 2022
By Catherine Longworth
Freenome Holdings Inc. has landed $290 million from Basel, Switzerland-based Roche Holding AG to advance its multiomics platform for early cancer detection. The multimillion financing deal brings San Francisco-based Freenome’s total funding to more than $1.1 billion, securing its status as a unicorn company. It comes on the heels of a series D raise in December 2021, which netted Freenome $300 million from investors including Perceptive Advisors and RA Capital Management.
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Product image

Rebus’ spatial omics platform minimizes hands-on time

March 1, 2021
By Annette Boyle
Rebus Biosystems Inc. introduced the first commercially available spatial omics platform at the Advances in Genome Biology and Technology virtual meeting on March 1. The Rebus Esper builds on the company’s Synthetic Aperture Optics (SAO) technology that enables rapid quantitative analysis of tens of millions of cellular features across hundreds of thousands of cells in their native tissue contexts.
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Bluestar Genomics, University of Chicago see publication of 5hmC map

Dec. 2, 2020
By Liz Hollis
Bluestar Genomics Inc. and the University of Chicago revealed the publication of a genome-wide 5-hydroxymethylcytosine (5hmC) map across multiple human tissue types. In the report, published Dec. 2, 2020, in Nature Communications, the researchers detailed the development of the map by characterizing the genomic distributions of 5hmC in 19 human tissues derived from 10 organ systems.
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Difference in image resolution with Synthetic Aperture Optics vs. standard

Rebus Biosystems raises $20M in series B round

Nov. 20, 2020
By Annette Boyle
Rebus Biosystems Inc. has closed a $20 million series B fundraising round. The financing round was led by Illumina Ventures with participation by Lifecore Partners, Ncore Ventures, Xolon Invest, Ctk Investments, Ray Co. Ltd., Seegene Medical Foundation, Labgenomics Co. Ltd. and Timefolio Asset Management. Rebus builds spatial omics tools, assays and platforms. The company plans to use the new funding to support commercialization of its spatial omics solution and expansion of its marketing, sales, research, and product development teams, said Rebus CEO Paul Sargeant. Rebus plans to launch its automated, standalone Rebus Biosystems instrument and optimized assay kits for spatial transcriptomics early in 2021.
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Diagram illustration

Lifetime Initiative provides roadmap to transformation of European health care through interceptive medicine

Sep. 9, 2020
By Annette Boyle
The Lifetime Initiative released a roadmap to revolutionize health care in Europe by implementing cell-based interceptive medicine in a perspective article published Sept. 7 in Nature.
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NIH's Collins: All of Us initiative should be fully enrolled by 2022

Sep. 12, 2019
By Mark McCarty
Francis Collins, director of the U.S. NIH, said in a public forum that the agency is "really bullish" about precision medicine. However, while precision medicine requires mounds of data, which soon may be available, Collins said the NIH All of Us research program has drawn the interest of more than 300,000 willing participants to date, adding that the target enrollment of 1 million should be accomplished before the end of 2022.
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