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BioWorld - Monday, January 26, 2026
Home » Topics » Clinical

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Digital lungs illustration

Bioversys, Shionogi in CHF529M lung infection collaboration

July 2, 2025
By Nuala Moran
No Comments
Antibiotics specialist Bioversys AG has sealed a potential CHF529 million (US$667.5 million) deal with Shionogi Co. Ltd., in which they will work together on novel ansamycins for treating multidrug-resistant lung infections caused by non-tuberculous mycobacteria.
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Beckley Atai deal to go forth on positive phase IIb depression data

July 1, 2025
By Nuala Moran
No Comments
The joining of psychedelic specialists Beckley Psytech Ltd. and Atai Life Sciences can now go ahead after the pair announced positive top-line results from the phase IIb study of BPL-003, an intranasal formulation of 5-MeO-DMT benzoate.
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Syringe in front of Moderna logo

With new flu data, Moderna reconsiders its COVID combo

June 30, 2025
By Lee Landenberger
No Comments
Solid phase III efficacy results for Moderna Inc.’s seasonal influenza vaccine, mRNA-1010, may lead the company to resubmit a BLA for a flu/COVID-19 combo shot it has been developing. The top-line data showed Moderna’s flu vaccine produced a superior relative efficacy that was 26.6% higher than a comparator standard-dose seasonal influenza vaccine in people ages 50 and older.
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Elderly hands holding broken brain structure

Xpro phase II miss as Inmune’s Mindful tunes in to AD subgroup

June 30, 2025
By Randy Osborne
No Comments
Inmune Bio Inc. claimed a phase II win with TNF inhibitor Xpro (pegipanermin) in early Alzheimer’s disease (AD), though the study missed its primary and secondary endpoints, leading shares of the firm (NASDAQ:INMB) to close at $2.16, down $3.18, or almost 60%.
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Biopharma clinical updates May 2025

Sleep apnea, cancer and obesity drugs lead May phase III wins

June 27, 2025
By Amanda Lanier
No Comments
BioWorld tracked 223 clinical trial updates across phases I to III in May 2025, marking an increase from 197 in March and 151 in April. Among these, 17 trials reported positive phase III results, while two ended in failure and another two delivered mixed outcomes.
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Liver illustration

Altimmune’s phase IIb in MASH hits and misses, stock halves

June 26, 2025
By Lee Landenberger
No Comments
Top-line results from Altimmune Inc.’s phase IIb Impact study of pemvidutide in treating metabolic dysfunction-associated steatohepatitis showed the peptide-based GLP-1/glucagon dual receptor agonist hit one primary endpoint while not hitting statistical significance in another.
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Product image
ADA 2025

In-patient BYOD still troublesome for CGM makers

June 25, 2025
By Annette Boyle
With a growing number of people wearing continuous glucose monitors and an ever-shrinking number of hospital-based nurses, bringing your own device or using personal CGMs to measure glucose levels during hospitalizations seems like a no-brainer.
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Cervical cancer cell

UK Women to be offered home-testing kits for cervical screening

June 24, 2025
By Shani Alexander
The U.K. government will offer women home-testing kits for cervical screening as part of an effort to tackle barriers and get more of them taking this potentially life-saving test.
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Pregnancy
ADA 2025

AID system improves glycemic control in pregnancy

June 24, 2025
By Annette Boyle
Pregnant women with type 1 diabetes who used a hybrid closed loop automated insulin delivery system averaged more than three additional hours per day in their recommended glucose range than those who managed their diabetes with insulin injections or non-automated pump systems, a study presented at the 85th Scientific Sessions of the American Association in Chicago demonstrated.
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Xia Jin, CEO and co-founder of Immuno Cure, and Dan Mallon, senior vice president of corporate development for Pharmajet

Immuno Cure, Pharmjet partner on needle-free HIV vaccine trial

June 24, 2025
By Tamra Sami
No Comments
Immuno Cure Biotech Ltd. is collaborating with Pharmajet Inc. to evaluate the safety and immunogenicity of its HIV therapeutic DNA vaccine, Icvax, delivered via Pharmajet's innovative Tropis needle-free injection system.
Read More
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