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BioWorld - Saturday, March 14, 2026
Home » Topics » Clinical

Clinical
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Biopharma clinical updates June 2024

Roche’s Columvi and GSK’s Blenrep among 23 phase III successes in June

July 30, 2024
By Amanda Lanier
In June 2024, BioWorld covered 221 clinical trial updates, compared to 298 in May. BioWorld recorded 23 phase III trial successes in June, seven failures, and one with mixed results.
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WHO preps for human avian flu spread with mRNA vaccine project

July 30, 2024
By Mari Serebrov
With the COVID-19 pandemic still visible in the rearview mirror, the World Health Organization (WHO) is taking no chances as it preps for human avian influenza, or H5N1, a subtype of influenza A.
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Close up image of shoulder and back with severe urticaria or hives

CIndU breakthrough? Celldex phase II scores with barzolvolimab

July 30, 2024
By Randy Osborne
Succeeding where others have failed in an indication with high unmet need, Celldex Therapeutics Inc. disclosed top-line data from the phase II trial with barzolvolimab (barzo) against two common forms of chronic inducible urticaria (CIndU): cold urticaria (ColdU) and symptomatic dermographism (SD).
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Ovarian cancer gene therapy shows promise; Imunon preps for phase III

July 30, 2024
By Karen Carey
Phase II data showing an 11.1-month improvement in overall survival for advanced ovarian cancer patients treated with the IL-12 immunotherapy IMNN-001 drove up shares of Imunon Inc. by 181% July 30. The results “could usher in the first immune-based therapy for ovarian cancer,” said Stacy Lindborg, president and CEO of the Lawrenceville, N.J.-based company.
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Waveview bc diagnostic
Patents

Wave View patenting microwave technology for pain-free, timely breast imaging

July 29, 2024
By Simon Kerton
The first patenting to be published in the name of Wave View Imaging Inc. sees its co-founders file for additional protection of their imaging technology which can be used to monitor breast cancer treatment.
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Biopharma clinical updates June 2024

Roche’s Columvi and GSK’s Blenrep among 23 phase III successes in June

July 29, 2024
By Amanda Lanier
In June 2024, BioWorld covered 221 clinical trial updates, compared to 298 in May. BioWorld recorded 23 phase III trial successes in June, seven failures, and one with mixed results.
Read More

Stick to TYK2? Ventyx says no after miss in mid-stage Crohn’s bid

July 29, 2024
By Randy Osborne
Another failure with allosteric tyrosine kinase 2 (TYK2) inhibitor VTX-958 put an end to internal work with the compound, and shares of Ventyx Biosciences Inc. (NASDAQ:VTYX) fell July 29 to $2.24, down 71 cents or 24%, after the firm disclosed results from the phase II, 109-subject trial in moderately to severely active Crohn’s disease (CD).
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Elderly hands holding broken brain structure

Despite endpoint miss, Cognition sees path forward in Alzheimer’s

July 29, 2024
By Jennifer Boggs
Cognition Therapeutics Inc. said it is moving to the next stage of clinical testing with oral, small-molecule candidate CT-1812, despite phase II efficacy results falling short of statistical significance in patients with mild to moderate Alzheimer’s disease and sending shares of the Purchase, N.Y.-based company (NASDAQ:CGTX) falling 44%, or $1.04, to close July 29 at $1.33.
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Boston Scientific Farapulse PFS system

Boston Scientific’s Farapulse reduces NHS costs

July 26, 2024
By Shani Alexander
The first economic modelling of Boston Scientific Corp.’s pulsed field ablation system in U.K.’s National Health Service showed that it is more cost-effective as a treatment for paroxysmal atrial fibrillation compared to standard cryoablation.
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Feet and scale

Viking presses obesity programs forward, delighting investors

July 25, 2024
By Lee Landenberger
Viking Therapeutics Inc. is diving more deeply into developing obesity treatments and investors like an accelerated timetable the company has proposed. On June 25, Viking shares (NASDAQ:VKTX) catapulted 28.3% upward to close at $64.68 each.
Read More
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