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BioWorld - Saturday, August 1, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Poseida’s adventure continues, CAR T cruising to positive phase I data in mCRPC

Aug. 31, 2021
By Randy Osborne
Questions regarding rates of cytokine release syndrome (CRS) cropped up during Poseida Therapeutics Inc.’s conference call on preliminary data from nine patients in the company’s phase I trial of P-PSMA-101, an autologous CAR T product candidate to treat patients with metastatic castrate-resistant prostate cancer (mCRPC).
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New class of Mcl-1 inhibitors developed at Janssen for treating myeloma

Aug. 31, 2021

Low-dose targeted radionuclide therapy using [90Y]NM-600 promotes response to ICIs

Aug. 31, 2021

New benzimidazole derivative as a selective RORgamma inverse agonist for prostate cancer treatment

Aug. 31, 2021

TroBio Therapeutics presents new compounds for cancer

Aug. 31, 2021

Janssen Biotech divulges DHODH inhibitors

Aug. 31, 2021
Artificial intelligence and digital health icons

Researchers develop AI application able to predict 10-year prostate cancer mortality

Aug. 30, 2021
By Bernard Banga
PARIS – Researchers from the department of radiation oncology at the European Hospital Georges Pompidou (HEGP) and Stanford University School of Medicine have together developed a new artificial intelligence (AI) prediction tool for patients diagnosed with prostate cancer. These researchers have just published a validation of this interpretable AI model in Cancers. “It’s a question of distinguishing patients at risk of mortality from aggressive cancer that is spreading rapidly, from patients who might have far less aggressive cancer and who are not likely to die from it in under 10, 15 or even 20 years,” Jean-Emmanuel Bibault, radiotherapy oncologist at HEGP, told BioWorld.
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Cancer cell and DNA
Newco news

Binhui moves HSV-2-based oncolytic viral candidate toward U.S. trial

Aug. 30, 2021
By Doris Yu
Binhui Biopharmaceutical Co. Ltd.’s BS-001, a recombinant human oncolytic herpes simplex virus type-2 expressing GM-CSF for the potential treatment of solid tumors, has gained an IND approval from the FDA. The development marks the first oncolytic viral candidate developed by a Chinese company to win a go-ahead for trials abroad, it said.
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TH-1902, a new docetaxel-peptide conjugate with efficacy in SORT1-positive TNBC models

Aug. 30, 2021

CELMoD CC-99282 for hematological malignancies

Aug. 30, 2021
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