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BioWorld - Thursday, June 25, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Pharmaengine inks partnership with Sentinel Oncology for checkpoint kinase 1 inhibitor SOL-578

Dec. 9, 2020
By Gina Lee
HONG KONG – Taipei, Taiwan-based Pharmaengine Inc. has signed a collaboration and licensing deal with Cambridge, U.K.-based Sentinel Oncology Ltd. for the latter’s checkpoint kinase 1 inhibitor, SOL-578. Through the agreement, Sentinel will receive an exclusivity payment and Pharmaengine will fund the IND-enabling studies.
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Software screenshot

Paige obtains CE marks for breast, prostate cancer options

Dec. 9, 2020
By Liz Hollis
Paige has received good news in the EU, securing a CE mark for its breast cancer detection software that highlights suspicious areas for pathologists to review further. It also received a CE mark for Paige Prostate Grading & Quantification, which offers slide level information for primary and secondary Gleason patterns and tumor size to inform treatment planning.
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FDA clears IND for first-in-human study of KB-0742 for MYC-amplified tumors

Dec. 9, 2020

Teligene identifies new protein kinase inhibitors

Dec. 9, 2020

ACSS2 inhibitors discovered at Metabomed

Dec. 9, 2020

ION-251 enters first-in-human trial for relapsed or refractory multiple myeloma

Dec. 9, 2020

Enrollment open in phase Ib/II study of KRT-232 with acalabrutinib in DLBCL and CLL

Dec. 9, 2020

Jacobio initiates first-in-human study of JAB-8263 in advanced solid tumors

Dec. 9, 2020

Nuvation conducts phase I/II study of NUV-422 in recurrent or refractory high-grade gliomas

Dec. 9, 2020
Leukemia illustration

Curis ‘blasts’ off, thanks to AML/MDS phase I data

Dec. 8, 2020
By Randy Osborne
Questions of durability came up regarding Curis Inc.’s latest data with CA-4948, but that didn’t stop shares from soaring to $6.55 by day’s end, an increase of $5.11, or 355%. The ride came after Lexington, Mass.-based Curis rolled out positive preliminary data from the firm’s ongoing open-label, single-arm phase I dose-escalation study with the compound.
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