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BioWorld - Wednesday, July 15, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Merck taps Janux in $1B+ cancer collaboration

Dec. 18, 2020
By Lee Landenberger
In what could end up being a deal that tops $1 billion, Merck & Co. Inc. cut a collaboration and license agreement with Janux Therapeutics to find, develop and commercialize T cell engager immunotherapies for cancer patients.
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Black Diamond, others ‘pan’ fish with wide-net inhibitors

Dec. 18, 2020
By Randy Osborne
In the second half of November, Black Diamond Therapeutics Inc. gained attention from Wall Street by nominating BDTX-1535 as the firm’s development candidate for glioblastoma multiforme (GBM) and kicked off IND-enabling studies.
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Cancer cell and DNA

HSF1 inhibition directly targets treatment-resistant prostate cancer

Dec. 18, 2020
By John Fox
Scientists at Duke University School of Medicine in Durham, North Carolina, have developed a small-molecule inhibitor of the cellular stress-protective transcription factor, heat shock factor 1 (HSF1), which showed developmental promise against treatment-resistant prostate cancer and other cancers.
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Illustration of mtDNA
Bench Press

Potentiating PARP inhibitors

Dec. 18, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: Studying the role of mtDNA expression.
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First-in-human data presented for AB-928 with or without IPI-549 in patients with cancer

Dec. 18, 2020

STP-938, a novel CTPS1 inhibitor with activity in hematological malignancies

Dec. 18, 2020

Ideaya Biosciences discloses POLH inhibitors

Dec. 18, 2020

Angex Pharmaceutical presents new PRMT5 inhibitors

Dec. 18, 2020

Agios Pharmaceuticals synthesizes new MAT2A inhibitors

Dec. 18, 2020

VioGen Biosciences patents new PIKfyve inhibitors

Dec. 18, 2020
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