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BioWorld - Monday, December 8, 2025
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Gears with regulatory words

OIG won’t oppose drugmaker payment for companion diagnostic

July 11, 2025
By Mark McCarty
Companies in the life sciences must tread carefully when it comes to the Anti-Kickback Statute, but a recent advisory opinion by the Office of Inspector General lends little clarity on the point.
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Circode executives
Newco news

Circode applies circRNA to heart disease drug R&D, in vivo CAR T

July 11, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
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Cancer

Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 11, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
Read More
Cancer

Dana Farber and Stanford patent molecular glue degraders

July 11, 2025
Dana Farber Cancer Institute Inc. and Stanford University have patented new molecular glue degraders comprising cereblon (CRBN) binding moiety acting as casein kinase 1 isoform α and/or wee1-like protein kinase (Wee1) degradation inducers reported to be useful for the treatment of cancer.
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Cancer

Nikang Therapeutics and Shanghai Blueray Biopharma synthesize GTPase KRAS mutant inhibitors

July 11, 2025
Researchers from Nikang Therapeutics Inc. and Shanghai Blueray Biopharma Co. Ltd. have discovered GTPase KRAS (G12D mutant) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Incyte discloses new bicyclooctane KRAS inhibitors

July 11, 2025
No Comments
Incyte Corp. has described GTPase KRAS (mutant) inhibitors reported to be useful for the treatment of cancer, inflammatory and immunological disorders.
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Prostate cancer cells
Cancer

Study uncovers the role of RNF126 as a driver of prostate cancer progression

July 11, 2025
No Comments
Prostate cancer is one of the most common male-related cancers, and understanding the underlying mechanisms is crucial for developing new treatment strategies and avoiding resistance development.
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Hands holding gears
Cancer

Mitsubishi Tanabe Pharma forms targeted alpha therapy collaboration in Japan

July 11, 2025
No Comments
Mitsubishi Tanabe Pharma Corp., Veneno Technologies Co. Ltd. and Alpha Fusion Co. Ltd. have initiated a joint research collaboration in Japan to develop cancer drugs using targeted alpha therapy (TAT).
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PTAB hands Exact a loss in Geneoscopy patent dispute

July 10, 2025
By Mark McCarty
The med tech patent wars opened a new front in the region of screening tests for colorectal cancer, pitting Exact Sciences Corp., of Madison, Wisc., against St. Louis-based Geneoscopy Inc.
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Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 10, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
Read More
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