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BioWorld - Thursday, December 25, 2025
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Sinotau Pharmaceutical Groups office

Sinotau nets $152M in financing to develop radiopharmaceuticals in China

July 5, 2023
By Doris Yu
Sinotau Pharmaceutical Group raised ¥1.1 billion (US$152 million) in a financing round to develop its radiopharmaceutical drugs for diagnostic and therapeutic interventions.
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Aveir DR dual-chamber leadless pacemaker

Abbott snares FDA approval for leadless, dual-chamber Aveir pacemaker

July 5, 2023
By Mark McCarty
Leadless cardiac electrophysiology devices have been around for a while now, but Abbott Laboratories of Abbott Park, Ill., has managed to beat the competition in the market for dual chamber pacing via two leadless devices. The company reported July 5 that the U.S. FDA has approved the Aveir DR, a two-unit device configuration that provides pacing for both the right ventricle and the right atrium and which some analysts believe helps to make Abbott shares an underappreciated asset for investors.
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Sinotau Pharmaceutical Groups office

Sinotau nets $152M in financing to develop radiopharmaceuticals in China

July 3, 2023
By Doris Yu
Sinotau Pharmaceutical Group raised ¥1.1 billion (US$152 million) in a financing round to develop its radiopharmaceutical drugs for diagnostic and therapeutic interventions.
Read More
Illustration of heart and lung vasculature in pulmonary hypertension vs. normal
Cardiovascular

Zymedi collaborates with NHLBI to advance ZMA-001 for pulmonary arterial hypertension

July 3, 2023
Zymedi Co. Ltd. has signed a clinical cooperative research and development agreement (CRADA) with the National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), to develop ZMA-001 for the treatment of pulmonary arterial hypertension (PAH).
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Jonathan Paul and Osmanuddin Ahmed

Flow Medical nears completion of catheter to treat venous thromboembolic disease

June 30, 2023
By David Godkin
University of Chicago spinoff Flow Medical Inc. is finalizing its design of a multi-function catheter to diagnose and treat venous thromboembolic disease – boosted by a $1 million private investment to commercialize the device.
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Blood pressure cuff

European Society of Hypertension recommends renal denervation as a treatment for hypertension

June 30, 2023
By Shani Alexander
The European Society of Hypertension (ESH) has recommended that renal denervation (RDN) be offered as an adjunctive therapy to patients with resistant hypertension. Releasing new and updated guidelines on the management of arterial hypertension, the ESH said recent randomized controlled trials showed that endovascular RDN can be associated with a significant, albeit not marked, office and ambulatory blood pressure reduction in patients with uncontrolled hypertension.
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Drug R&D concept image.
Cardiovascular

Drug Farm’s ALPK1 inhibitor DF-003 cleared by FDA to enter clinic

June 30, 2023
Drug Farm has received FDA clearance of its IND application for DF-003, a first-in-class, oral, potent, highly selective ALPK1 inhibitor.
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Savvy at in-licensings, Edding Group files for Hong Kong IPO

June 26, 2023
By Marian (YoonJee) Chu
Edding Group Co. Ltd. announced June 23 it filed for an IPO on the Hong Kong Exchange – news that comes amid a steep drop in China’s biopharma IPO market forecasting sluggish activity in a near-frozen “capital winter.”
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Heart scientific overlay
Cardiovascular

MMP-12 inhibitor shows potential in a cardiac sarcoidosis mouse model

June 26, 2023
Investigators from Foresee Pharmaceuticals Co. Ltd., Medical University of Vienna and Cleveland Clinic recently reported data on the effects of the matrix metalloproteinase-12 (MMP-12) inhibitor FP-020 in a mouse model of cardiac sarcoidosis in which chronic activation of mTORC1 signaling in myeloid cells causes spontaneous cardiac sarcoid-like granulomas.
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Cardiovascular

Advances in regenerative medicine for cardiovascular repair

June 23, 2023
By Mar de Miguel
Over the past decade there has been much research into the use of induced pluripotent stem cells (iPSCs) as a cell therapy to regenerate tissue and treat heart disease. Now, one researcher has narrowed the focus down to treating heart disease not with whole cells, but with mitochondria derived from iPSCs. Gentaro Ikeda, a researcher at the Department of Medicine at Stanford University, has worked on generating extracellular vesicles (EVs) containing mitochondria from pluripotent stem cell-derived cardiomyocytes and administering these to restore the functionality of the myocardium in a porcine model of an infarct.
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