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BioWorld - Monday, March 30, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Heart, DNA and ECG
Cardiovascular

Rejuvenate Bio’s gene therapy shows promise in mouse model of arrhythmogenic cardiomyopathy

Oct. 10, 2023
Rejuvenate Bio Inc. has released new preclinical efficacy data for its gene therapy, RJB-0402, in a mouse model of arrhythmogenic cardiomyopathy (ACM), an inherited disease caused by mutations in one of several genes encoding desmosomal proteins.
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Cardiovascular

Switching back the metabolism of cardiomyocytes stimulates heart regeneration

Oct. 6, 2023
By Mar de Miguel
Just one week after birth, the heart experiences a change in metabolism that helps it meet the high energy demand necessary to fulfill its function. This evolutionary developmental process could have medical advantages.
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transcardiac access port
Patents

Connex Biomedical reveals its platforms for transcardiac access and device delivery

Oct. 5, 2023
By Simon Kerton
Connex Biomedical Inc. applied for patent protection for a transcardiac access port affixed and retained post-procedure on the cardiac muscle, such as the ventricular myocardium, and an access port delivery system configured to deliver the access port, secure the access port to the muscle tissue with tissue anchors, and provide a working channel through the access port to facilitate transcardiac access and device delivery.
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acoustic blood flow sensor
Patent

Canary sings praises of acoustic blood flow sensors for remotely monitoring heart conditions

Oct. 3, 2023
By Simon Kerton
Canary Medical Inc. is seeking patent protection for devices, systems, and methods for in vivo monitoring of the flow of a biological fluid in an anatomic structure.
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Cyclopharm Technegas

FDA approves Cyclopharm’s Technegas combo product for visualizing pulmonary ventilation

Oct. 2, 2023
By Tamra Sami

After a long and bumpy path to approval, the U.S. FDA has finally given the green light to Cyclopharm Ltd’s Technegas combination product a day after the Sept. 29 PDUFA date.


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Cyclopharm Technegas

FDA approves Cyclopharm’s Technegas combo product for visualizing pulmonary ventilation

Oct. 2, 2023
By Tamra Sami
After a long and bumpy path to approval, the U.S. FDA has finally given the green light to Cyclopharm Ltd’s Technegas combination product a day after the Sept. 29 PDUFA date.
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Selution SLR

Cordis completes $1B+ Medalliance buy heavily weighted toward future milestones

Oct. 2, 2023
By Annette Boyle

Cordis Corp. covered its bets a bit as it closed the acquisition of M.A. Med Alliance SA (Medalliance) announced almost a year ago. While the total payment for the company could total $1.135 billion, it could take six years for the owners of privately held Medalliance to see most of the funds.


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Cyclopharm Technegas

FDA approves Cyclopharm’s Technegas combo product for visualizing pulmonary ventilation

Oct. 2, 2023
By Tamra Sami

After a long and bumpy path to approval, the U.S. FDA has finally given the green light to Cyclopharm Ltd’s Technegas combination product a day after the Sept. 29 PDUFA date.


Read More
Vascular system
Cardiovascular

Evotec and Novo Nordisk launch Lab En2 translational drug discovery accelerator for cardiometabolic diseases

Sep. 27, 2023
Evotec SE and Novo Nordisk A/S have announced the launch of Lab En2, a translational drug discovery accelerator that aims to advance early research from academic institutions into novel therapeutics.
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Cardiovascular

Novo Nordisk and Valo Health collaborate on drug discovery and development in cardiometabolic diseases

Sep. 26, 2023
Novo Nordisk A/S and Valo Health Inc. have entered into an agreement to discover and develop novel treatments for cardiometabolic diseases. The collaboration will leverage Valo’s Opal Computational Platform, including access to real-world patient data, artificial intelligence (AI)-enabled small-molecule discovery and Biowire human tissue modeling platform designed to speed up the discovery and development process.
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