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BioWorld - Friday, April 24, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Small extracellular vesicle
Cancer

Clots and metastasis in cancer patients start in the lung

Feb. 20, 2025
By Mar de Miguel
The lung and thrombosis may play a key role in cancer and metastasis progression, according to a collaborative study led by Cornell University scientists. In the nonmetastatic lung microenvironment of several cancer types, the development of a prothrombosis niche promotes metastasis formation through the release of small extracellular vesicles loaded with an integrin protein.
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Tinted Euro symbol

Cardiovascular, robotics and AI attract European VCs

Feb. 19, 2025
By Shani Alexander
Med-tech companies focusing on cardiovascular diseases or neurological conditions, women’s health or robotic surgery, will find European investors willing to deploy capital into their stories. European venture capital firms are excited about the continuing innovation and opportunities in the sector.
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Cardiovascular illustration
Cardiovascular

Integrin α5β1 is target for pulmonary arterial hypertension

Feb. 19, 2025
Researchers from Morphic Therapeutic Inc. and affiliated organizations published data from a study that aimed to assess the potential of using arginylglycylaspartic acid (RGD) integrins for the treatment of cardiovascular diseases, such as pulmonary arterial hypertension (PAH).
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Solid rocks DMD space with phase I/II gene therapy data

Feb. 18, 2025
By Randy Osborne
Solid Biosciences Inc. is preparing for a sit-down with the U.S. FDA this year to discuss the firm’s results with the next-generation gene therapy SGT-003 for Duchenne muscular dystrophy (DMD).
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VAripulse

J&J resumes US Varipulse sales, but will it matter?

Feb. 18, 2025
By Annette Boyle
Nearly six weeks after Johnson & Johnson paused the U.S. external evaluation of its Varipulse pulsed field ablation catheter to investigate several neurovascular events in initial cases, the med-tech giant resumed its limited market release with revised global instructions for use.
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Dongkook hq

Dongkook Life Science secures ₩18B IPO

Feb. 18, 2025
By Marian (YoonJee) Chu
Dongkook Life Science Co. Ltd. (DKLS) priced a ₩18 billion (US$12.5 million) IPO on the Korea Exchange as South Korea’s first med-tech listing of the year.
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Ziwig Endotest

France grants Ziwig Endotest fast-track reimbursement

Feb. 13, 2025
By Annette Boyle
Ziwig SAS, which leads the race for a simple diagnostic for endometriosis, picked up the pace with a fast-track reimbursement decision in France for its Endotest, the first saliva-based diagnostic assay for endometriosis.
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Colorful illustration of the heart
Cardiovascular

Parkin activation through PR-364 preserves cardiac function after acute MI in preclinical models

Feb. 13, 2025
Heart disease remains the leading cause of death worldwide, and developing new therapeutic approaches constitutes an urgent healthcare priority. Almost one-third of patients surviving myocardial infarction (MI) develop heart failure (HF), in part due to damage caused by the accumulation of dysfunctional mitochondria.
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Device in heart

Edwards: TAVR wavers, mitral valve shines

Feb. 12, 2025
By Annette Boyle
Edwards Lifesciences Corp.’s posted fourth quarter results slightly ahead of expectations, but indicated that the first quarter of 2025 might not be as bright. The company expects growth for both its lead transcatheter aortic valve replacement (TAVR) business and the company to fall below its full-year estimates, with a mid-year indication expansion for TAVR providing a critical boost in the back half of 2025.
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mri-safety
Patents

Northwestern is harnessing AI for real-time MRI safety assessment

Feb. 12, 2025
By Simon Kerton
A recent patent application from Laleh Rad, associate professor of Biomedical Engineering and Radiology at Northwestern University, describes the use of machine learning for real-time risk assessment of magnetic resonance imaging in patients with conductive implants for whom tissue heating from radiofrequency excitation fields remains a major concern.
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