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BioWorld - Thursday, February 5, 2026
Home » Topics » Disease categories and therapies » Gastrointestinal

Gastrointestinal
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IMEC ingestible GI sensor
Patents

IMEC seeks ingestible GI sensor patent

July 9, 2025
By Simon Kerton
Researchers from IMEC, the Netherlands’ OnePlanet Research Center in Wageningen, filed for protection of an inexpensive, highly miniaturized ingestible device that may be used for remotely activatable sampling, gut health monitoring and drug delivery.
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Hand pointing at digital M&A screen

Torrent Pharma to buy JB Pharma from KKR in $3B M&A deal

July 1, 2025
By Marian (YoonJee) Chu
No Comments
Torrent Pharmaceutical Ltd. will buy J. B. Chemicals and Pharmaceuticals Ltd. (JB Pharma) from private equity firm KKR & Co. Inc. at an equity valuation of ₹256.89 billion (US$3 billion), which will then merge into one entity under Torrent Pharma.
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Liver illustration

Altimmune’s phase IIb in MASH hits and misses, stock halves

June 26, 2025
By Lee Landenberger
No Comments
Top-line results from Altimmune Inc.’s phase IIb Impact study of pemvidutide in treating metabolic dysfunction-associated steatohepatitis showed the peptide-based GLP-1/glucagon dual receptor agonist hit one primary endpoint while not hitting statistical significance in another.
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Businessman and IPO virtual screen

Caris settles IPO at $21, trading starts at $28

June 20, 2025
By Annette Boyle
Despite raising the price of its IPO twice, Caris Life Sciences Inc. left money on the table with a 33% increase in price as soon as trading commenced on the Nasdaq, though no one is squawking about raising nearly $500 million. The cancer diagnostics company initially priced its IPO at $16 to $18, then raised it to $19 to $20, before closing on a price of $21 per share. As management rang the bell for the start of trade on June 18, shares began trading at $28.
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Illustration of intestines with inflammation
Gastrointestinal

Engineered anti-IL-23 receptor antibody enables oral delivery to treat inflammatory bowel disease

June 19, 2025
No Comments
Researchers from Genentech Inc. have developed a novel single-domain antibody (VHH) targeting the IL-23 signaling pathway, which can be administered orally to effectively treat inflammatory bowel disease in animal models.
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Model of fecal microbiota transplantation with glowing microbiota flowing between a donor and recipient
Gastrointestinal

Gut microbiome leads to metabolic and immune changes after transplant

June 13, 2025
By Mar de Miguel
No Comments
Is fecal microbiota transplant effective? Is it really safe? And is it really all the same? Scientists at the University of Chicago have investigated the regional differences in gut environments to question these interventions.
Read More
Gastrointestinal

Korean scientists divulge new ADAMTS4 inhibitors for hepatic fibrosis

June 13, 2025
Researchers at Gachon University and Seoul National University Hospital have synthesized a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4; aggrecanase-1) inhibitors reported to be useful for the treatment of hepatic fibrosis.
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Gastrointestinal

New LPAM-1 antagonists disclosed in Dice Molecules patent

June 12, 2025
Dice Molecules SV LLC has divulged integrin α4β7 (LPAM-1) antagonists reported to be useful for the treatment of graft-vs.-host disease, type 1 diabetes, inflammatory bowel disease, colitis and primary sclerosing cholangitis.
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Model of fecal microbiota transplantation with glowing microbiota flowing between a donor and recipient
Gastrointestinal

Gut microbiome leads to metabolic and immune changes after transplant

June 11, 2025
By Mar de Miguel
No Comments
Is fecal microbiota transplant effective? Is it really safe? And is it really all the same? Scientists at the University of Chicago have investigated the regional differences in gut environments to question these interventions to analyze the microbiome differences and their effects after transplantation form different intestine areas. The results show how host-microbe mismatches after these interventions could affect gut health.
Read More
Model of fecal microbiota transplantation with glowing microbiota flowing between a donor and recipient
Gastrointestinal

Gut microbiome leads to metabolic and immune changes after transplant

June 10, 2025
By Mar de Miguel
No Comments
Is fecal microbiota transplant effective? Is it really safe? And is it really all the same? Scientists at the University of Chicago have investigated the regional differences in gut environments to question these interventions to analyze the microbiome differences and their effects after transplantation form different intestine areas. The results show how host-microbe mismatches after these interventions could affect gut health.
Read More
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