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BioWorld - Thursday, April 23, 2026
Home » Topics » Disease categories and therapies » Gastrointestinal

Gastrointestinal
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Microscope with beakers and flasks
Gastrointestinal

Enveda Biosciences raises financing to advance anti-inflammatory programs

June 17, 2024
Enveda Biosciences (Enveda Therapeutics Inc.) has announced a new series B2 financing round of $55 million. The drug discovery and development company uses artificial intelligence (AI)-powered technologies to translate nature into new medicines.
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Illustration of intestines with inflammation

Futuregen joins Abbvie in $1.7B inflammatory bowel disease deal

June 14, 2024
By Lee Landenberger
Through a global rights agreement with Futuregen Biopharmaceutical Co. Ltd., Abbvie Inc. continues to build its immunology portfolio to help offset losses from Humira as biosimilars tighten their grip on the mega-blockbuster.
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Gastrointestinal

Abbvie licenses Futuregen’s next-generation TL1A antibody for inflammatory bowel disease

June 14, 2024
Abbvie Inc. and Futuregen Biopharmaceutical (Beijing) Co. Ltd. have signed a license agreement to develop FG-M701, a next-generation TL1A antibody for the treatment of inflammatory bowel disease.
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Nexsphere

Drug-device developer Next Biomedical files for Kosdaq IPO

June 12, 2024
By Marian (YoonJee) Chu
Incheon, South Korea-based Next Biomedical plans to offer one million shares on the Korea Exchange at a price band of ₩24,000 (US$17.42) to ₩29,000 per share. The IPO is scheduled for August 2024 and expected to raise ₩24 billion to ₩29 billion.
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Gastrointestinal

Roche presents HIF-2α inhibitors for inflammatory bowel disease

June 12, 2024
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have described hypoxia inducible factor-2α (HIF-2α; EPAS1) inhibitors reported to be useful for treatment of ulcerative colitis and Crohn’s disease.
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Ipsen wins FDA nod for Iqirvo in primary biliary cholangitis

June 11, 2024
By Jennifer Boggs
Ipsen SA picked up U.S. FDA accelerated approval for its Genfit SA-licensed elafibranor, making it the first new drug in eight years for treating primary biliary cholangitis, though a potential competitor lurks just around the corner.
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AI-generated illustration of enzyme activity
Endocrine/metabolic

Syntis Bio advances oral enzyme replacement therapies toward IND filing

June 11, 2024
Syntis Bio Inc. has announced its launch, with a focus on advancing a pipeline of oral therapies engineered for optimization in the small intestine and a portfolio of enzyme replacement therapies to treat orphan metabolic and broad digestive disorders.
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Epigenetics concept art.
Cancer

EASL 2024: Epigenetics as door to liver cancer treatment

June 10, 2024
By Coia Dulsat
Throughout the 2024 annual congress of the European Association for the Study of the Liver (EASL), held in Milan last week, almost all basic tracks included some reference to epigenetics, or changes to the chromatin that affect how accessible a gene is to the transcription machinery.
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Liver illustration
Gastrointestinal

Novel 17β-HSD13 inhibitor reduces fibrosis and steatosis in a MASH model

June 7, 2024
In metabolic dysfunction-associated steatohepatitis (MASH) preclinical models, absence of the lipid droplet-associated protein hydroxysteroid 17β dehydrogenase 13 (17β-HSD13) has been identified as protective against liver fibrosis.
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Human liver cell.
Gastrointestinal

EASL 2024: Hepatocyte journey across liver disease and beyond

June 7, 2024
By Coia Dulsat
The ongoing European Association for the Study of the Liver 2024 congress in Milan opened yesterday with several presentations on cell plasticity and its role in liver function and regeneration in chronic liver disease situations.
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