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BioWorld - Wednesday, February 25, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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SK Bioscience CEO Jaeyong Ahn and head of Sanofi Vaccines GBU Thomas Triomphe

Another challenger in pediatric PCV as SK Bio posts positive data for 21-valent vaccine

June 30, 2023
By Marian (YoonJee) Chu
SK Bioscience Ltd. and Sanofi Pasteur SA announced June 30 positive results from a phase II study for its 21-valent pneumococcal conjugate vaccine (PCV) candidate called GBP-410, or SP-0202 under Sanofi.
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Influenza virus
Infection

Poolbeg Pharma identifies influenza drug targets through AI program with Cytoreason

June 30, 2023
Poolbeg Pharma plc has announced the discovery of multiple influenza drug targets through an artificial intelligence (AI)-led program.
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Infection

Scripps Research Institute discovers new antiviral prodrugs for SARS-CoV-2

June 29, 2023
Scripps Research Institute has described nucleoside analogues acting as prodrugs reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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Infection

Grant supports Exevir Bio’s preclinical research on prophylactic and therapeutic solutions for dengue

June 29, 2023
Exevir Bio BV has been awarded a 2-year R&D grant of €1.6 million by Flanders Innovation & Entrepreneurship (VLAIO) for preclinical research towards prophylactic and therapeutic solutions for dengue.
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Colorized transmission electron micrograph of an mpox virus particle
Immune

Blue Water Biotech reports preclinical data on use of norovirus S&P VLP platform to develop mpox vaccine

June 29, 2023
Blue Water Biotech Inc. has released preliminary preclinical data supporting the use of its norovirus shell and protrusion (S&P) virus-like particle (VLP) platform to develop a novel mpox vaccine candidate.
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Infection

siRNA PD-L1 inhibition leads to HBV infection clearance

June 28, 2023
One of the characteristics of chronic hepatitis B virus (HBV) infection is T-cell exhaustion, which, in turn, is mediated by the PD-1/PD-L1 axis. Researchers at Oligo Therapeutics Inc. reported on ALG-072571, a potent siRNA PD-L1 inhibitor active against HBV infection mouse models.
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Drug vial and syringe
Immune

SARS-CoV-2/flu two-hit protective vaccine developed based on RBD conjugated with inactivated influenza A virus

June 28, 2023
SARS-CoV-2 and influenza (flu) viruses share similar clinical manifestations, common transmission mechanisms and target tissues, often overlapping during seasonal outbreaks. In addition, co-infection of these viruses worsens disease severity, emphasizing the pressing need for a vaccine that effectively tackles both.
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Transmission electron microscopic image of hepatitis B virus.
Infection

HBV antisense oligonucleotide AHB-137 exerts potent antiviral activity in vivo

June 28, 2023
Recent studies in chronic hepatitis B patients have shown that bepirovirsen, an antisense oligonucleotide (ASO), may be considered a suitable option for the treatment of hepatitis B virus (HBV) infection.
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Shionogi to acquire Qpex for $140M to expand antimicrobial pipeline

June 27, 2023
By Tamra Sami
Shionogi & Co. Ltd.’s U.S. subsidiary Shinogi Inc. will acquire San Diego-based Qpex Biopharma Inc. in a deal worth up to $140 million that expands Shionogi’s pipeline of infectious disease agents and also adds to Brii Biosciences Ltd.’s pipeline.
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HIV/AIDS

Gilead Sciences discovers new prodrugs of lenacapavir for HIV

June 27, 2023
Gilead Sciences Inc. has described soluble prodrugs of lenacapavir reported to be useful for the treatment of HIV infection.
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