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BioWorld - Wednesday, December 31, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Female researcher wearing mask and safety glasses holding dropper

APACMed sees urgent need to harmonize regs for LDTs across APAC

Jan. 31, 2025
By Tamra Sami
Harmonized regulations for laboratory-developed tests (LDTs) across Asia Pacific are sorely needed at a time when LDTs continue to play a critical role in addressing unmet needs in the region, according to a recent whitepaper developed by APACMed.
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Structural model of dengue virus.
Infection

Chugai and GSK collaborate to advance AID-351 for dengue

Jan. 31, 2025
Chugai Pharmaceutical Co. Ltd. has signed a collaboration agreement with GSK plc’s Global Health Unit (GSK GH) for the development of an anti-dengue virus antibody. Under this agreement, GSK GH will perform activities and explore potential funding for the initiation of clinical studies of AID-351.
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Inflammatory

Chinese researchers describe JX-06’s effects in multiple organ injury

Jan. 30, 2025
Multiple organ dysfunction syndrome is a life-threatening condition derived from heat stress or sepsis, among other conditions, that can lead to irreversible organ damage and death if left untreated. Gasdermin (GSDMD) is an executor protein that causes cell lysis, facilitates the release of inflammatory mediators and is involved in pyroptosis, apoptosis and necroptosis processes leading to inflammatory cell death or PANoptosis.
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Child vaccine
Analysis

The science on vaccines and autism: no there there

Jan. 29, 2025
By Anette Breindl
At his confirmation hearing, Robert F. Kennedy Jr., the nominee for secretary of the U.S. Department of Health and Human Services, claimed that he is not anti-vaccine. But his record does not bear that out. Kennedy is a longstanding vaccine denier, and in 2021 was identified as one of the “Disinformation Dozen” – the 12 accounts responsible for the majority of disinformation about COVID-19 vaccines on social media platforms – by the British-American nonprofit Center for Countering Digital Hate.
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RFK Senate hearing 1-29-25

Confirmation hearings begin for RFK as US HHS secretary

Jan. 29, 2025
By Mari Serebrov
In a U.S. Senate Finance Committee confirmation hearing marked by shouted protests, outbursts of applause and tense exchanges on several issues, including ones beyond the reach of the Department of Health and Human Services (HHS), Robert F. Kennedy Jr. (RFK) tried to present himself as someone who follows the science, not a conspiracy theorist or anti-vaxxer.
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Ebola virus
Infection

Discovery of optimized antiviral candidates against Ebola and Marburg viruses

Jan. 28, 2025
Ebola virus and Marburg virus are single-stranded, enveloped and negative sense-RNA viruses belonging to the Filoviridae family, and they both cause deadly hemorrhagic fevers in humans and mammals.
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Illustration of teen boy with acne on face caused by Cutibacterium acnes
Infection

New antimicrobial peptides with broad-spectrum activity against Cutibacterium acnes

Jan. 28, 2025
Over-colonization and subsequent inflammation triggered by Cutibacterium acnes is the primary factor in the pathogenesis of acne vulgaris, a prevalent skin condition among adolescents. Gyeongsang National University has discovered and characterized new antimicrobial peptides (AMPs) as candidates for the treatment of acne vulgaris.
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Colorized transmission electron micrograph of SARS-CoV-2.
Immune

Ocugen’s OCU-500 inhaled mucosal vaccine for COVID-19 gains IND clearance

Jan. 27, 2025
Ocugen Inc. has received IND clearance from the FDA for OCU-500, an inhaled mucosal vaccine for COVID-19. The National Institute of Allergy and Infectious Diseases (NIAID) will sponsor and conduct a phase I trial of OCU-500 administered via inhalation into the lungs and intranasally as a spray.
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Vaxxas HD-MAP Administration

Vaxxas, CEPI advance program for thermostable mRNA vaccines

Jan. 24, 2025
By Tamra Sami
Vaxxas Pty. Ltd. and the Coalition for Epidemic Preparedness Innovations are progressing heat-stable, dried-formulation mRNA vaccines using Vaxxas’ needle-free high-density microarray patch.
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Illustration of blood cells, Plasmodium causing malaria illness
Infection

TKK-130 is novel antiplasmodial agent

Jan. 24, 2025
Researchers from Heinrich-Heine-Universität Düsseldorf (HHUD) and affiliated organizations presented the discovery of novel antimalarial agents.
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