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BioWorld - Wednesday, February 18, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 14, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
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CDC headquarters

US CDC nomination withdrawn, reforms in the works

March 13, 2025
By Mari Serebrov
Shortly before the Senate Health, Education, Labor and Pensions Committee was to hold the first ever confirmation hearing for a U.S. CDC director March 13, it issued a statement saying the hearing was canceled due to the White House withdrawing its nomination of Dave Weldon, a physician and former congressman from Florida.
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Transmission electron micrograph of HIV-1 virus particles
HIV/AIDS

SP-38 potently inhibits HIV-1 replication by inducing defective particle morphology

March 13, 2025
It was previously demonstrated that the HIV-1 integrase (IN)-interacting host factor INI1/SMARCB1 binds to HIV-1 IN through its Rpt1 domain of INI1 (INI1-Rpt1) and plays a key role in assembly and particle production.
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 13, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
Read More
Vaccine vial and syringe

Aim seeks approval of first serum-free human rabies vaccine

March 12, 2025
By Marian (YoonJee) Chu
Aim Vaccine Co. Ltd. may become the first company to gain regulatory clearance of a prophylactic iterative serum-free human rabies vaccine. Beijing-based Aim said it is preparing a regulatory submission of its independently developed rabies vaccine based on positive phase III results that showed good safety, immunogenicity and immune persistence.
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Genome concept art.
Infection

Study looks to noncoding gene variants for new drug targets

March 12, 2025
By Nuala Moran
A new multi-omics approach to unpicking how noncoding gene variants influence the development of common chronic diseases has identified tens of thousands of instances where variants have an impact on gene expression levels and gene splicing, the post-transcriptional modification that allows one gene to code for multiple proteins.
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Leyden Labs raises $70M for intranasal flu drugs, acquires Covbio

March 11, 2025
By Marian (YoonJee) Chu
Leyden Laboratories BV added a fresh $70 million in financing to advance Panflu, its phase II-ready intranasal pan-influenza prophylactic medicine, while acquiring Cov Biotechnology Pte. Ltd. (Covbio) and its zoonotic virus-targeting portfolio to prepare for the next pandemic.
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HIV infected cell
HIV/AIDS

At CROI, HIV cure trials raise hopes for broader applicability

March 11, 2025
By Anette Breindl
At the 2025 meeting of the Conference on Retroviruses and Opportunistic Infections (CROI) it was the best of times, it was the worst of times. On the first full day of the conference, reports from the first HIV cure trial conducted in Africa, the RIO trial and others showed that perhaps, a broadly useful cure is on the horizon.
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Blood cells and bacteria
Infection

New organ-targeted antimicrobial agent for the treatment of systemic infections and pyelonephritis

March 11, 2025
Researchers from Shaanxi Panlong Pharmaceutical Group Co. Ltd., Shaanxi Pioneer Biotech Co. Ltd. and affiliated organizations presented the discovery and preclinical characterization of novel pleuromutilin antibiotics, designed as organ-targeted, multimechanism antimicrobial agents using organic cation transporter (OCT)-mediated transport.
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Gloved hand holding vial, syringe
Infection

Using computational biology to develop pan-H5 vaccine against avian influenza

March 11, 2025
Researchers from Diosynvax Ltd. presented data from a study that aimed to evaluate the efficacy of a pan-H5 vaccine designed using computational biology and being developed for protection against avian influenza.
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