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Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 15, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
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Medical art concept for radicular leg pain or sciatic nerve pain

Seikagaku’s Ferring-partnered condoliase for pain wins at adcom

Jan. 14, 2025
By Randy Osborne
Data from two out of three positive studies faced the U.S. FDA’s Anesthetic and Analgesic Drug Products Advisory Committee as members examined the package submitted by Seikagaku Corp., of Tokyo, for SI-6603 (condoliase), a chemonucleolytic drug for radicular leg pain associated with lumbar disc hernia.
Read More
Illustration of man holding magnifying glass to human body model showing muscle anatomy
Neurology/psychiatric

Targeted exon-skipping strategy restores dysferlin function in muscular dystrophy model

Jan. 14, 2025
Recent work proposes a promising therapeutic approach for dysferlinopathies.
Read More
Medical art concept for radicular leg pain or sciatic nerve pain

Seikagaku’s Ferring-partnered condoliase for pain wins at adcom

Jan. 10, 2025
By Randy Osborne
Data from two out of three positive studies faced the U.S. FDA’s Anesthetic and Analgesic Drug Products Advisory Committee as members examined the package submitted by Seikagaku Corp., of Tokyo, for SI-6603 (condoliase), a chemonucleolytic drug for radicular leg pain associated with lumbar disc hernia.
Read More
Musculoskeletal

Series A financing at Rheumagen supports HLA gene-editing therapies for autoimmune diseases

Jan. 10, 2025
The financing will enable progression of RG-0401.
Read More
Celosia team
Neurology/psychiatric

Australia’s Celosia heads toward clinic with gene therapy for ALS

Jan. 8, 2025
By Tamra Sami
After raising AU$16.75 million (US$10.4 million) in a series A round, Celosia Therapeutics Pty Ltd. is heading toward the clinic with its novel gene therapy that targets TDP-43, a protein directly linked to amyotrophic lateral sclerosis (ALS) pathology.
Read More
Celosia team
Newco news

Australia’s Celosia heads toward clinic with gene therapy for ALS

Jan. 7, 2025
By Tamra Sami
After raising AU$16.75 million (US$10.4 million) in a series A round, Celosia Therapeutics Pty Ltd. is heading toward the clinic with its novel gene therapy that targets TDP-43, a protein directly linked to amyotrophic lateral sclerosis (ALS) pathology.
Read More
Celosia team
Newco news

Australia’s Celosia heads toward clinic with gene therapy for ALS

Jan. 3, 2025
By Tamra Sami
After raising AU$16.75 million (US$10.4 million) in a series A round, Celosia Therapeutics Pty Ltd. is heading toward the clinic with its novel gene therapy that targets TDP-43, a protein directly linked to amyotrophic lateral sclerosis (ALS) pathology.
Read More
Musculoskeletal

Epirium’s MF-300 cleared to enter clinic for sarcopenia

Dec. 24, 2024
Epirium Bio Inc. has obtained IND clearance from the FDA for MF-300, a first-in-class orally administered, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) enzyme inhibitor.
Read More
Musculoskeletal

Mitsubishi Tanabe Pharma describes new SIK inhibitors

Dec. 20, 2024
Mitsubishi Tanabe Pharma Corp. has identified serine/threonine-protein salt-inducible kinases (SIK) inhibitors reported to be useful for the treatment of psoriatic arthritis, lupus nephritis, osteoarthritis, pancreatitis, rheumatoid arthritis, Sjögren’s syndrome, systemic lupus erythematosus and ulcerative colitis, among others.
Read More
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