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BioWorld - Monday, May 4, 2026
Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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Nucleotide’s in: Gene therapy high water lifts Affinia with $60M series A

April 1, 2020
By Randy Osborne
The allure of gene therapy was proved yet again as Waltham, Mass.-based Affinia Therapeutics Inc. bagged an oversubscribed $60 million series A financing to boost the push for drugs to benefit people affected by muscle and central nervous system conditions.
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Butyrate affects regulatory B cells, rheumatoid arthritis

March 31, 2020

Roche synthesizes new TLR7/TLR8/TLR9 antagonists

March 30, 2020

Phase I data with inzomelid support progression to phase II

March 26, 2020
U.S. money

Design Therapeutics raises $45M to take on degenerative disorders

March 20, 2020
By Michael Fitzhugh
Design Therapeutics Inc., a San Diego startup developing new therapies for degenerative disorders caused by nucleotide repeat expansions, has raised $45 million in series A financing.
Read More

Aclaris initiates phase IIa study of ATI-450 with methotrexate for moderate to severe RA

March 16, 2020

Roche patents Toll-like receptor antagonists

March 13, 2020

Positive results presented from phase Ib portion of PREVAIL study of PRV-3279

March 13, 2020

New mouse model of Charcot arthropathy

March 13, 2020

Archimedes entreaties: Needful FSHD world to move via Fulcrum bid with losmapimod?

March 10, 2020
By Randy Osborne
With a phase IIb readout coming in the third quarter of 2020, Cambridge, Mass.-based Fulcrum Therapeutics Inc. might be set up for a win in facioscapulohumeral muscular dystrophy (FSHD), a genetic muscle disorder for which there’s no treatment.
Read More
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