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Home » Topics » Disease categories and therapies » Neonatal/pediatrics

Neonatal/pediatrics
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3d illustration of human body muscle tissue anatomy
Musculoskeletal

Benfotiamine improves dystrophic pathology in mice

Aug. 8, 2024
Researchers from Royal Children's Hospital, the University of Melbourne and affiliated organizations published data from a study that aimed to investigate the potential of benfotiamine, which is a lipid soluble precursor to thiamine, for the treatment of inflammation related dystrophic pathology in patients with Duchenne muscular dystrophy (DMD).
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Child feet
Cancer

Medannex awarded funding to study therapy in pediatric osteosarcoma

July 26, 2024
Medannex Ltd. has been awarded an Innovate UK grant to fund a £313,000 (US$403,000) project developing a new treatment for pediatric osteosarcoma. Innovate UK will fund £231,000 (US$297,000) of the project costs, with the remainder financed by Medannex.
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Photo of hands holding a baby
Neurology/psychiatric

URB-447 confers neuroprotection after neonatal hypoxia-ischemia in rats

July 12, 2024
One of the most common causes of adverse neurological disabilities in newborns is neonatal hypoxic-ischemic encephalopathy. Therapeutic hypothermia (TH) is the standard therapy, but it is not efficient in all cases. Cannabinoids have raised interest as therapeutics as they are neuroprotective.
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Concept art for prenatal genetic testing and whole genome sequencing.
Genetic/congenital

ASGCT: In utero interventions can prevent organ damage after birth

May 9, 2024
By Mar de Miguel
“Prenatal therapies are the next disruptive technologies in health care, which will advance and shape the future of patient care in the 21st century,” said Graça Almeida-Porada, a professor at the Fetal Research and Therapy Center of the Wake Forest Institute for Regenerative Medicine in Winston-Salem, North Carolina. At the American Society of Gene & Cell Therapy (ASGCT) annual meeting in Baltimore on May 5, 2024, Almeida-Porada introduced the first presentation of the scientific symposium “Prospects for Prenatal Gene and Cell Therapy.”
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Medically accurate illustration of a baby in the womb of a pregnant mother
Cardiovascular

Peripartum cardiomyopathy is associated with placental senescence

April 24, 2024
By Mar de Miguel
Scientists at Massachusetts General Hospital have linked the risk of heart failure during pregnancy and senescence proteins produced by placental aging, which could clarify how peripartum cardiomyopathy (PPCM) is triggered and opens the door to the development of cardiac function therapies in late pregnancy.
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NICU beanie
Patents

Beanie hat protects hearing of babies in NICUs, encourages development

March 27, 2024
By Simon Kerton
In what represents its first patenting, Sonura LLC has been issued with a patent for an aural device designed to protect the hearing of infants in a neonatal intensive care unit (NICU) by active filtering, while, at the same time, providing aural stimulation for neurological development.
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3D illustration of organoid models in a petri dish
Neonatal/Pediatrics

3D organoids arising from amniotic fluid cells may be a potent prenatal tool

March 8, 2024
By Xavier Bofill Bruna
Organoids are 3D models created from human stem cells and resemble fetal tissues. In an article published in Nature Medicine on March 4, 2024, researchers from University College London provided details on the possibility of generating organoids from epithelial cells collected from amniotic fluid without terminating the pregnancy.
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Neonatal/Pediatrics

3D organoids arising from amniotic fluid cells may be a potent prenatal tool

March 5, 2024
By Xavier Bofill Bruna
Organoids are 3D models created from human stem cells and resemble fetal tissues. In an article published in Nature Medicine on March 4, 2024, researchers from University College London provided details on the possibility of generating organoids from epithelial cells collected from amniotic fluid without terminating the pregnancy.
Read More
Infant examination
Gastrointestinal

Neurenati Therapeutics secures funding to advance candidate for Hirschsprung’s disease

March 1, 2024
Neurenati Therapeutics has closed its seed funding round, securing CA$1.2 million (US$884,000) to advance development of therapies for various rare diseases, including pediatric conditions.
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Brain, illustrating pain/injury
Neurology/Psychiatric

New pediatric rat model of DFP-induced status epilepticus

Feb. 6, 2024
Researchers from Texas A&M University System have detailed the development and characterization of a novel pediatric rat model of organophosphate (OP)-induced status epilepticus (SE).
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