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BioWorld - Sunday, July 3, 2022
Home » Topics » Ocular, BioWorld

Ocular, BioWorld
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Rays of light beaming from eye

Delivering the goods: Regenxbio, Adverum explore alternate routes in AMD

Aug. 14, 2020
By Randy Osborne
No Comments
Earlier this month, an update on phase I/IIa data rolled out from Rockville, Md.-based Regenxbio Inc. with RGX-314 for age-related wet macular degeneration (AMD). The company has a pivotal program in subretinal delivery of the compound set to start by the end of this year, and questions about routes of administration – always an issue in AMD – continue to simmer.
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China’s Arctic Vision to tap into first-in-class ophthalmology products after deal with Eyenovia

Aug. 13, 2020
By Bryan Wong
No Comments
HONG KONG – China’s Arctic Vision Biotechnology Co. Ltd. has entered into an exclusive deal with New York-based Eyenovia Inc. to develop and commercialize ophthalmic formulations that are delivered using the latter’s first-in-class microdosing spray technology.
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Iacta Pharmaceuticals and Zhaoke Ophthalmology agree to co-develop novel eye treatments

July 30, 2020
By David Ho and Elise Mak
No Comments
HONG KONG - California-based Iacta Pharmaceuticals Inc. and Hong Kong-based Zhaoke Ophthalmology Pharmaceutical Ltd. have inked a definitive license agreement for two of Iacta’s products.
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Shanghai, China, stock market illustration

China’s Sunshine Guojian prices $240M IPO on STAR, shares jump 92% on first day

July 22, 2020
By Bryan Wong
No Comments
HONG KONG – Looking to boost its R&D capacity, China’s Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. launched an IPO on July 22 that raised ¥1.7 billion (US$240 million) on Shanghai’s STAR market. Shares (SSE:688336) almost doubled in value on the first day of trading, closing at ¥54.10, for a gain of 92%.
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Arctic Vision closes $32M series A to move lead product to clinic

July 15, 2020
By Bryan Wong
No Comments
HONG KONG – Chinese eye disease specialist Arctic Vision (Shanghai) Biotechnology Co. Ltd. raised $32 million in a series A financing round to advance its lead program, ARVN-001 (triamcinolone acetonide suprachoroidal injectable suspension), for treating macular edema associated with uveitis and to bolster its R&D.
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Harbour Biomed closes $102.8M series C to advance late-stage programs

July 10, 2020
By Elise Mak
No Comments
BEIJING – Known for its transgenic mouse platforms to develop antibodies, U.S., China and the Netherlands-based Harbour Biomed Therapeutics Ltd. closed a series C funding round July 9 to raise $102.8 million to advance its late-stage clinical programs and COVID-19 pipeline.
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Hong Kong stock market illustration

HKEX gains Ocumension as its fifth biotech IPO this year

July 6, 2020
By Bryan Wong
No Comments
HONG KONG - Ocumension Therapeutics Ltd., a China-based ophthalmic pharmaceutical company, launched its IPO on the Hong Kong Exchange (HKEX) this week. The company seeks to raise more than HK$1.5 billion (US$190 million).
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Close-up of eye with digital focus

FDA issues CRL to wet AMD drug from Allergan, Molecular Partners

June 26, 2020
By Lee Landenberger
No Comments
The FDA sent a complete response letter (CRL) to Allergan plc, an Abbvie Inc. company, and Molecular Partners AG, of Zurich, Switzerland, regarding the BLA for abicipar pegol, their VEGF-A inhibitor-Darpin therapy for patients with wet age-related macular degeneration (AMD).
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Close-up of eye with digital focus

Opthea’s OPT-302 meets primary endpoints in phase IIa diabetic macular edema trial

June 10, 2020
By Tamra Sami
No Comments
PERTH, Australia – Melbourne, Australia-based Opthea Ltd. announced positive top-line results of its phase IIa trial evaluating safety and efficacy of OPT-302 administered with Eylea (aflibercept, Regeneron Pharmaceuticals Inc.) in treatment-refractory patients with persistent diabetic macula edema (DME).
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Eye drops

Oculis hits endpoints in phase IIb trial of OCS-01 in cataract surgery

May 18, 2020
By Nuala Moran
No Comments
LONDON – Oculis SA has delivered positive phase IIb data for OCS-01, a topical nanoparticle formulation of dexamethasone, in the treatment of the after-effects of cataract surgery, meeting the primary endpoints of reducing both inflammation and pain.
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