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BioWorld - Wednesday, January 28, 2026
Home » Topics » Drugs » Small molecule

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Two arrows in opposite directions

Gilead ends $785M Yuhan deal for small-molecule MASH drugs

Oct. 15, 2024
By Marian (YoonJee) Chu
Gilead Sciences Inc. terminated a potential $785 million licensing deal with Yuhan Corp. inked in 2019 to develop metabolic dysfunction-associated steatohepatitis (MASH) therapies.
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Innocare’s TYK2 inhibitor meets psoriasis endpoints in phase II

Oct. 15, 2024
By Tamra Sami
Innocare Pharma Ltd.’s tyrosine kinase 2 (TYK2) inhibitor, ICP-488, met the primary endpoint in a phase II trial in Chinese patients with moderate to severe plaque psoriasis, and the results clear the way to accelerate clinical development in psoriasis and other autoimmune diseases.
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Gold Euro symbol on blue background

Amid shifting MASH landscape, Inventiva adds €348M financing

Oct. 15, 2024
By Nuala Moran
Inventiva SA is back on course to complete phase III development of its metabolic dysfunction-associated steatohepatitis (MASH) drug, lanifibranor, after putting in place new financing of up to €348 million (US$379.4 million), including an immediate cash injection of €94.1 million.
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Two arrows in opposite directions

Gilead ends $785M Yuhan deal for small-molecule MASH drugs

Oct. 11, 2024
By Marian (YoonJee) Chu
Gilead Sciences Inc. terminated a potential $785 million licensing deal with Yuhan Corp. inked in 2019 to develop metabolic dysfunction-associated steatohepatitis (MASH) therapies.
Read More

Innocare’s TYK2 inhibitor meets psoriasis endpoints in phase II

Oct. 10, 2024
By Tamra Sami
Innocare Pharma Ltd.’s tyrosine kinase 2 (TYK2) inhibitor, ICP-488, met the primary endpoint in a phase II trial in Chinese patients with moderate to severe plaque psoriasis, and the results clear the way to accelerate clinical development in psoriasis and other autoimmune diseases.
Read More
Scientist, microscope and dropper
Cancer

Bayer and Moma Therapeutics collaborate on small-molecule oncology program

Oct. 9, 2024
Bayer AG and Moma Therapeutics Inc. have entered into a collaboration, under an option and exclusive license agreement, to develop and commercialize a small-molecule oncology program.
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Seniors with wooden puzzle

Sage stumbles in Alzheimer’s while awaiting Huntington’s data

Oct. 8, 2024
By Lee Landenberger
Bad news has buffeted Sage Therapeutics Inc. twice in the past few months. Now its placebo-controlled phase II Lightwave study of dalzanemdor in Alzheimer's disease has missed the primary outcome measure, prompting the company to stop development of the NMDA receptor positive allosteric modulator in the indication.
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IPO stock market ticker

Caliway’s $206M IPO marks largest in Taiwan’s biotech history

Oct. 8, 2024
By Tamra Sami
Taiwan’s Caliway Biopharmaceuticals Co. Ltd. raised NT$6.4 billion (US$206 million) in its IPO on the Taipei Stock Exchange, making it the largest IPO in Taiwan’s biotech industry history and valuing the company at nearly $3 billion following the listing.
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Test tubes, dropper and capsules
Cardiovascular

CSPC Pharmaceutical licenses rights for Lp(a) inhibitor to Astrazeneca

Oct. 8, 2024
CSPC Pharmaceutical Group Ltd. has entered into an exclusive license agreement with Astrazeneca plc for the global development, manufacture and commercialization of CSPC’s lipoprotein(a) (Lp[a]) inhibitor, YS-2302018, and any pharmaceutical or biological product subsequently developed that includes the compound.
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IPO stock market ticker

Caliway’s $206M IPO marks largest in Taiwan’s biotech history

Oct. 4, 2024
By Tamra Sami
Taiwan’s Caliway Biopharmaceuticals Co. Ltd. raised NT$6.4 billion (US$206 million) in its IPO on the Taipei Stock Exchange, making it the largest IPO in Taiwan’s biotech industry history and valuing the company at nearly $3 billion following the listing.
Read More
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