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BioWorld - Sunday, December 21, 2025
Home » Topics » Drugs » Vaccine

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Therapeutic trends 2024 - infectious diseases

In 2024, pandemic breakthroughs were for better and for worse

Dec. 24, 2024
By Anette Breindl, Mar de Miguel, and Annette Boyle
First, the good news about pandemics – and in 2024, there was big “good news.” Science Magazine named lenacapavir (Gilead Sciences Inc.) as the Breakthrough of the Year. In two separate trials, lenacapavir prevented HIV transmission with 100% efficacy in cisgender African women and 99.9% efficacy in men and gender-diverse persons when administered twice a year.
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Photo of Jaeyong Ahn and Jean-Francois Toussant in signing ceremony

Sanofi expands SK Bio deal, starts phase III of GBP-410

Dec. 23, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd. won €50 million (₩75.5 billion, US$52.03 million) up front from Sanofi SA to expand an earlier agreement to develop and commercialize novel pneumococcal conjugate vaccines (PCVs). The first deal resulted in GBP-410 (SP-0202), its pediatric 21-valent PCV candidate that moved into phase III study last week.
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SK Bioscience scientist in lab

SK Bioscience to start mRNA vax trial for Japanese encephalitis

Dec. 17, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd. gained approval from the Human Research Ethics Committee in Australia to start phase I/II trials of GBP-560, its mRNA-based vaccine candidate for mosquito-borne Japanese encephalitis virus, with funding from Coalition for Epidemic Preparedness Innovations.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 17, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 13, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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Immune

SK Bioscience’s mRNA Japanese encephalitis vaccine receives clinical trial clearance in Australia

Dec. 13, 2024
SK Bioscience has received approval from the Human Research Ethics Committee in Australia for a phase I/II trial of its mRNA-based Japanese encephalitis vaccine candidate, GBP-560.
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SK Bioscience scientist in lab

SK Bioscience to start mRNA vax trial for Japanese encephalitis

Dec. 12, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd. gained approval from the Human Research Ethics Committee in Australia to start phase I/II trials of GBP-560, its mRNA-based vaccine candidate for mosquito-borne Japanese encephalitis virus, with funding from Coalition for Epidemic Preparedness Innovations.
Read More
Scanning electron micrograph of Lassa virus budding off a cell.
Infection

INO-4500 provides long-lasting protection against Lassa fever

Dec. 12, 2024
Researchers from Inovio Pharmaceuticals Inc. described the protective effect exerted by INO-4500, a DNA vaccine produced using the Syncon technology, against lethal Lassa virus in nonhuman primates.
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Transmission electron micrograph of hepatitis B virus particles
Infection

Therapeutic hepatitis B vaccine generates robust HBc-specific T-cell responses in preclinical tests

Dec. 2, 2024
Researchers from presented preclinical data for AVX-70371, a novel therapeutic vaccine being developed for the treatment of chronic hepatitis B virus (HBV) infection.
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Woman about to receive a vaccine
Immune

CSPC’s HPV mRNA vaccine candidate cleared to enter clinic in China

Nov. 13, 2024
CSPC Pharmaceutical Group Ltd.’s SYS-6026 has obtained clearance from China’s National Medical Products Administration (NMPA) to enter clinical trials for the treatment of high-grade squamous intraepithelial lesions associated with human papillomavirus (HPV) type 16 or 18.
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