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BioWorld - Sunday, February 8, 2026
Home » Topics » Drugs » Vaccine

Vaccine
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CDC adopts ACIP recommendations for HBV vaccine

Dec. 17, 2025
No Comments
The U.S. CDC has adopted the recommendations of its Advisory Committee for Immunization Practices (ACIP) regarding the hepatitis B virus (HBV) vaccine scheduling for infants, determining that immunization should be an individual-based decision rather than the universal birth dosing practice that has been in place for the past 30 years.
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Person with chest pain after receiving a COVID-19 vaccine
Inflammatory

Research unpicks molecular mechanism of vaccine-induced cardiac inflammation

Dec. 12, 2025
By Anette Breindl
No Comments
The cardiomyositis that is a rare adverse effect of mRNA-based COVID vaccines is due to immune cell activity as a result of increased levels of the chemokines CXCL10 and interferon-γ (IFN-γ). Blocking CXCL10 and IFN-γ could prevent muscle cell damage in cell culture, and cardiomyositis in animal models. The findings, reported in the Dec. 10, 2025, issue of Science Translational Medicine, suggest a way of mitigating the risk of cardiomyositis.
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COVID-19 vaccine vials on conveyor belt

Petition claims FDA oops! means COVID-19 vaccines misbranded

Dec. 11, 2025
By Mari Serebrov
No Comments
Restricting the recommended use of COVID-19 vaccines in the U.S. wasn’t enough. Now the Children’s Health Defense (CHD) is trying to get the FDA to revoke the BLAs for all versions of the Moderna Inc. and Pfizer Inc.-Biontech SE COVID-19 vaccines.
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RFK at Senate HELP meeting 5-14

US lawmakers demand that Kennedy be held accountable

Dec. 10, 2025
By Mari Serebrov
No Comments
As the systematic dismantling of the U.S. vaccine schedule escalates, the demands to hold Health and Human Services Secretary Robert Kennedy accountable are growing. Claiming that Kennedy has turned his back on science and is endangering public health, Rep. Haley Stevens, D-Mich., formally introduced articles of impeachment against him Dec. 10 for “high crimes and misdemeanors.” Under the Constitution, federal officials can only be impeached for treason, bribery and “other high crimes and misdemeanors.”
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Mast cell releasing histamine during allergic response

Vaccine produces DIY Xolair-like antibody, protects against anaphylaxis

Dec. 10, 2025
By Anette Breindl
No Comments
Researchers at the Institut Pasteur have developed a vaccine that spurred the production of autoantibodies to immunoglobulin E antibodies, protecting vaccinated mice from anaphylaxis.
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Gloved hands holding mRNA vaccine vial
Immune

Korean consortium to develop mRNA vaccine for SFTS virus

Dec. 10, 2025
No Comments
A consortium including Korea Disease Control and Prevention Agency (KDCA), International Vaccine Institute (IVI), ST Pharm Co. Ltd. and Seoul National University (SNU) is joining forces with CEPI to advance a new AI-designed mRNA vaccine to protect against tick-borne severe fever with thrombocytopenia syndrome (SFTS) virus, or Dabie bandavirus. CEPI is providing up to US$16 million to the project, led by IVI, to test the vaccine’s safety and ability to generate a suitable immune response in healthy adults in preclinical and phase I/II trials in Korea.
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Mast cell releasing histamine during allergic response
Immune

Vaccine produces DIY Xolair-like antibody, protects against anaphylaxis

Dec. 9, 2025
By Anette Breindl
No Comments
Researchers at the Institut Pasteur have developed a vaccine that spurred the production of autoantibodies to immunoglobulin E (IgE) antibodies, protecting vaccinated mice from anaphylaxis. In their paper, which they published in Science Translational Medicine on Dec. 3, 2025, the authors noted that the polyclonal antibodies generated by their vaccine lasted “for up to 12 months postvaccination with a similar avidity as the approved anti-IgE mAb omalizumab [Xolair, Roche AG].”
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Vial and syringe with blue hues

Hippocratic loath? ‘Harm’ threat from ACIP’s proposed HBV shift

Dec. 5, 2025
By Randy Osborne
No Comments
Individual liberty and choice vs. wider public health became one predictable hinge upon which swung the often-acerbic debates at the CDC’s Advisory Committee for Immunization Practices (ACIP) meeting, which took up – again – the matter of hepatitis B virus (HBV) vaccine scheduling, a day after the panel voted not to vote on such guidance.
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Baby with bandage on thigh

Data-based concerns reveal consequence of hep B backsliding

Dec. 3, 2025
By Mari Serebrov
No Comments
“Do not take us backwards,” many doctors and other stakeholders implored the CDC’s Advisory Committee for Immunization Practices ahead of its meeting that starts Dec. 4 with a day-long discussion and votes on whether the current recommended birth dose of the hepatitis B virus vaccine should be delayed.
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Last-minute changes made ahead of ACIP meeting

Dec. 2, 2025
By Mari Serebrov
No Comments
U.S. Health and Human Services Secretary Robert Kennedy continued his last-minute musical chairs ahead of the Dec. 4-5 meeting of the Advisory Committee for Immunization Practices (ACIP) when he named Kirk Milhoan as the new chair of the panel that advises the CDC on vaccine schedules.
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