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BioWorld - Sunday, September 24, 2023
Home » Topics » Newco news

Newco news
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Hand holding money plant
Newco news

TVM invests $25M in new IgE-directed antibody allergy play

Feb. 9, 2023
By Cormac Sheridan
No Comments
TVM Capital Life Science has invested $25 million in Lamab Biologics Inc., which is taking forward a new twist on an old story in tackling allergic conditions. The asset-centric virtual company is developing a novel monoclonal antibody directed at immunoglobulin E (IgE) antibodies, which are responsible for mediating allergic responses.
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Digital cancer cells illustration
Newco news

Turbine’s cell simulation platform to probe unanswered questions in oncology

Feb. 3, 2023
By Cormac Sheridan
No Comments
Turbine Ltd. began the new year with a partnership with Cancer Research Horizons, the innovation arm of Cancer Research UK, which will put its Simulatedcell computational biology platform to work on the vexed question of how best to position CDC7 inhibitors in cancer.
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RNA strand
Newco news

Haya targets lncRNA for tissue-specific fibrosis drugs

Feb. 3, 2023
By Cormac Sheridan
No Comments
Could long non-coding RNAs be the key to developing organ-specific antifibrotic drugs that only mediate their effects in disease-related contexts? That’s the intriguing hypothesis that Haya Therapeutics SA has set out to explore, and its lead program, in heart failure caused by non-obstructive hypertrophic cardiomyopathy, is now in IND-enabling studies. A first clinical trial is pencilled in for late 2024 or early 2025.
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Glucose testing
Newco news

Clinical trial on horizon for company that restores the adipocyte

Jan. 31, 2023
By Caroline Richards
No Comments
After raising an undisclosed sum in a series A round, French biotech company Adipopharma LLC aims to progress its make-or-break targeted insulin resistance peptide into a phase I trial in type 2 diabetes patients by the end of 2023.
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Traditional Chinese medicine illustration
Newco news

ABVC Biopharma on the path to validating traditional medicine for the modern world

Jan. 31, 2023
By Tamra Sami
No Comments
ABVC Biopharma Inc is headquartered in San Francisco but it has its roots in Taiwan where it is digging into traditional medicine and validating it for the modern world. “There are a number of drugs that can’t be synthesized in the lab,” ABVC CEO Howard Doong told BioWorld, so he is going back to the original source of traditional Chinese medicines to validate them using traditional drug development models.
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Traditional Chinese medicine illustration
Newco news

ABVC Biopharma on the path to validating traditional medicine for the modern world

Jan. 25, 2023
By Tamra Sami
No Comments
ABVC Biopharma Inc is headquartered in San Francisco but it has its roots in Taiwan where it is digging into traditional medicine and validating it for the modern world. “There are a number of drugs that can’t be synthesized in the lab,” ABVC CEO Howard Doong told BioWorld, so he is going back to the original source of traditional Chinese medicines to validate them using traditional drug development models.
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Cross-section of a mouse lung infected with P. aeruginosa and treated with engineered M. pneumoniae
Newco news

Pulmobiotics is developing cell therapy for lung diseases, but with a twist

Jan. 19, 2023
By Anette Breindl
No Comments
Pulmobiotics Ltd., which was founded in 2019, is developing cell therapy for lung diseases, including lung cancer. But unlike other cell therapies for cancer, this one is based not on harnessing T cells but on engineering bacteria. The team has engineered Mycoplasma pneumoniae to deliver various therapeutic proteins to the lung, depending on the therapeutic indication.
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Stem cells
Newco news

Juvena looking to hESC-secreted proteins for treating age-related disease

Jan. 11, 2023
By Jennifer Boggs
No Comments
Juvena Therapeutics Inc. co-founder and CEO Hanadie Yousef had the company’s name picked out several years before it was officially incorporated in 2017 to combine Yousef’s work in the mechanics of aging with an underutilized class of biologics and an advanced proteomics platform to tackle chronic and age-related diseases.
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Silhouette made of crumpled paper illustrating depression
Newco news

Lusaris tackling treatment-resistant depression with neuroplastogen approach

Dec. 28, 2022
By Jennifer Boggs
No Comments
Over the past few years, the pandemic clearly has put a spotlight on vaccines and the infectious disease space. But the struggle to adjust in COVID-19’s wake also brought into stark relief another high unmet need. “Coming out of COVID, there was a mental health focus coming into play,” said Andrew Levin, partner and managing director at investment firm RA Capital Management who is also serving as interim CEO at Lusaris Therapeutics Inc., a 2021 startup targeting neuropsychiatric and neurological conditions, with an initial focus on treatment-resistant depression.
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T cells
Newco news

NXI Therapeutics reawakens interest in coronin-1 as autoimmune disease target

Dec. 19, 2022
By Cormac Sheridan
No Comments
Dialing down the immune response remains at the heart of myriad drug development efforts in autoimmune disease. Targeting cytokines, such as tumor necrosis factor alpha or interleukin-12 (IL-12) and IL-23, IL-6, or IL-17, or modulating immune cell trafficking by targeting sphingosine-1-phosphate receptor or integrins, are therapeutic mainstays. But chronic immunosuppression and all its attendant safety concerns is the price that many autoimmune disease patients pay to remain in remission.
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