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BioWorld - Tuesday, July 7, 2026
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Antibody-drug conjugates floating on light purple background

Gilead buying Tubulis and its ADCs in $5B takeover bid

April 7, 2026
By Karen Carey
No Comments
German company Tubulis GmbH, which emerged with a $12.3 million series A round and a next-generation antibody-drug conjugate (ADC) platform about six years ago, has commanded up to $5 billion in a buyout offer from Gilead Sciences Inc.
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Digital globe illustrating pharma trade, tariffs

Sector tariff now more than a threat – for some Rx companies

April 7, 2026
By Mari Serebrov
No Comments
After nearly a year of threats and promises of a global biopharma tariff of 25% to 500%, U.S. President Donald Trump finally delivered it. In the name of national security, he imposed a 100% sector tariff on prescription drugs and their associated ingredients beginning in about four months for large manufacturers and six months for smaller companies.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Neuropathy illustrated in legs and feet

Sononeu wins $5.2M ARPA-H grant for ultrasound-activated therapeutics

April 7, 2026
By Nuala Moran
No Comments
Newco Sononeu Inc. has launched to translate more than a decade of basic research in controlling cells with ultrasound into novel, non-invasive therapies for conditions including peripheral and diabetic neuropathy.
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Gavel and pill blister packs

Circuit split forming over state 340B laws

April 6, 2026
By Mari Serebrov
No Comments
Do state laws requiring drug companies to give steep 340B drug discounts to an unlimited number of contract pharmacies, with no claims data required, interfere with a longstanding contract between the U.S. Congress and biopharma? Or do such laws merely flex states’ authority over pharmacy practices such as delivery?
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Digital globe illustrating pharma trade, tariffs

Sector tariff now more than a threat – for some Rx companies

April 6, 2026
By Mari Serebrov
No Comments
After nearly a year of threats and promises of a global biopharma tariff of 25% to 500%, U.S. President Donald Trump finally delivered it. In the name of national security, he imposed a 100% sector tariff on prescription drugs and their associated ingredients beginning in about four months for large manufacturers and six months for smaller companies. However, depending on the drug, where it’s made and whether a manufacturer has reached onshoring and pricing agreements with the Department of Health and Human Services, the actual tariff could be as low as 0%.
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Vykat XR

Vykat caveat: Neurocrine’s $2.9B Soleno bid low-ball?

April 6, 2026
By Randy Osborne
No Comments
A proposal to buy out Soleno Therapeutics Inc. didn’t wait for European approval of Vykat XR (diazoxide choline) to treat hyperphagia in Prader-Willi syndrome, as Neurocrine Biosciences Inc. is putting on the table $53 per share in cash, which equates to an equity value of $2.9 billion.
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Eye and DNA illustration

LHON updates: Gene therapy progress; idebenone receives US CRL

April 2, 2026
By Marian (YoonJee) Chu
No Comments
Chiesi Group’s idebenone faced a regulatory setback last month after the U.S. FDA issued a complete response letter (CRL) to the company’s NDA for Leber hereditary optic neuropathy (LHON), a rare inherited disorder that causes sudden vision loss.But a chance missed for Chiesi may be an opportunity for gene therapies, including Gensight Biologics SA’s lenadogene nolparvovec (Lumevoq; GS-010).
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Connecting puzzle pieces
Neurology/psychiatric

Korsana boosts Alzheimer’s work with reverse merger, $380M financing

April 2, 2026
By Jennifer Boggs
No Comments
Just over a month after emerging from stealth and disclosing a $150 million series A, Korsana Biosciences Inc. is making the leap to the public market via a merger with Cyclerion Therapeutics Inc.  The agreement, which is backed by a $370 million private placement from Korsana’s investors, solidly positions the newly merged company as it heads toward the clinic with KRSA-028, a next-generation shuttled antibody targeting amyloid beta for the treatment of Alzheimer’s disease, and builds out a pipeline of neurodegenerative disease candidates.
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Trade secret theft results in loss of US citizenship

April 1, 2026
By Mari Serebrov
No Comments
On top of prison sentences, loss of assets and a $2.6 million restitution order issued several years ago, Li Chen and Yu Zhou had their naturalized U.S. citizenship revoked March 30 as a consequence of stealing exosome-related trade secrets from Nationwide Children's Hospital's Research Institute in Ohio – the hospital that had sponsored them when they first came to the U.S. from China on H-1B Specialty Occupation visas.
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