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BioWorld - Wednesday, May 20, 2026
Breaking News: Bundibugyo is harsh reminder of need for broad vaccine strategiesBreaking News: Tracking hantavirus across the globeBreaking News: Tracking hantavirus across the globe
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Respiratory

Chiesi Farmaceutici reports LPAR1 inhibitors for treatment of IPF

July 21, 2023
A Chiesi Farmaceutici SpA patent details cyclohexane acid derivatives acting as lysophosphatidic acid receptor 1 (LPAR1; EDG2) antagonists and thus reported to be useful for the treatment of idiopathic pulmonary fibrosis (IPF).
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Cancer

RIPK1 inhibitors detailed in Jeil Pharmaceutical patent

July 21, 2023
Jeil Pharmaceutical Co. Ltd. has identified receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of cancer, ulcerative colitis, rheumatoid arthritis, autoimmune disease, cardiovascular disorders and dermatological and inflammatory disorders and neurological disorders, among others.
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Cancer

Belgian and US researchers patent YAP/TAZ-TEAD interaction inhibitors

July 21, 2023
Katholieke Universiteit Leuven, Springworks Therapeutics Inc. and Vlaams Instituut voor Biotechnologie VZW have jointly patented...
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Vascular system
Cardiovascular

Riparian and Pfizer sign license and research agreement in cardiovascular disease

July 21, 2023
Riparian Pharmaceuticals Inc., a Viva Biotech Holdings Group portfolio company, has entered into an exclusive license agreement and research agreement with Pfizer Inc. in cardiovascular disease.
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Drug Design, Drug Delivery & Technologies

Chroma and Sangamo sign agreement on epigenetic medicines leveraging zinc finger proteins

July 21, 2023
Sangamo Therapeutics Inc. and Chroma Medicine Inc. have entered into a research evaluation, option and license agreement to develop epigenetic medicines leveraging zinc finger proteins (ZFPs) for sequence-specific DNA recognition.
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Pill over molecule structures
Inflammatory

Recludix and Sanofi collaborate on oral STAT6 inhibitors for immunological and inflammatory diseases

July 21, 2023
Recludix Pharma Inc. has entered into a strategic collaboration with Sanofi SA to develop and commercialize first-in-class oral small-molecule STAT6 (signal transducer and activator of transcription 6) inhibitors for patients with immunological and inflammatory diseases. STAT6 is believed to play a key role in multiple dermatological and respiratory diseases.
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Man piecing together a puzzle
Neurology/Psychiatric

KIT-13, a novel plasmalogen analogue effectively improves memory dysfunction in mice

July 21, 2023
Plasmalogens are a type of phospholipid that play significant roles in membrane fluidity and cellular processes such as vesicular fusion and signal transduction. Previous studies with natural plasmalogens have shown their role in neuroinflammation and memory function improvement.
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Gastrointestinal system with ulcerative colitis.
Gastrointestinal

Mage Biologics receives investment to develop oral monoclonal antibody targeting ulcerative colitis

July 21, 2023
Newly formed Mage Biologics Inc. is set to receive investment of $28 million from TVM Capital Life Science and Tillotts Pharma AG. Mage plans to advance to clinical proof of concept a novel, orally administered, humanized monoclonal antibody (MAb) for an initial indication of ulcerative colitis.
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Neurology/Psychiatric

PRX-123, a dual Aβ/tau peptide vaccine that clears Aβ plaques in brains of AD mice

July 21, 2023
Since both amyloid-β (Aβ) and tau are involved in the progression of Alzheimer’s disease (AD), it is believed that simultaneous disruption of these...
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A person receives the seasonal influenza vaccine.
Infection

MDCK-QIV influenza virus vaccine demonstrates safety and efficacy in preclinical setting

July 21, 2023
Researchers from Wuhan Institute of Biological Products Co. Ltd. and affiliated organizations presented preclinical data for the novel Madin...
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