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BioWorld - Tuesday, April 14, 2026
Breaking News: Best of BioWorld Science: Q1Breaking News: Best of BioWorld: Q1Breaking News: Best of BioWorld: Q1
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Nervous system illustration
Genetic/congenital

Cellatoz’s CLZ-2002 restores nerve myelination in preclinical Charcot-Marie-Tooth disease

May 22, 2024
Many patients with peripheral nerve diseases do not have a sufficient regenerative response because of genetic inheritance, infections or chronic disease, leading them to lifelong pain and disability.
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Radiotherapy of cancer
Cancer

Evergreen Theragnostics collaborates with Medical University of Innsbruck on radiopharmaceuticals

May 22, 2024
Evergreen Theragnostics Inc. has entered into a collaboration and licensing agreement with the Medical University of Innsbruck (MUI) to advance the development of novel radiopharmaceuticals.
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Hematologic

Optimized nonviral LNP system for hFVIII, P-FVIII-101, normalizes clotting efficacy in models of hemophilia A

May 22, 2024
Researchers from Poseida Therapeutics Inc. presented preclinical data for P-FVIII-101, a novel nonviral gene therapy being developed for the treatment of hemophilia A.
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Knee pain illustration
Neurology/psychiatric

Adolore Biotherapeutics makes progress with nonopioid analgesic gene therapies for chronic pain

May 22, 2024
Adolore Biotherapeutics Inc. has offered an update on recent pipeline development progress as it advances nonopioid analgesic gene therapies for the treatment of chronic pain.
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Endocrine/metabolic

Sixpeaks Bio emerges with pipeline of weight loss therapies

May 22, 2024
Sixpeaks Bio AG has emerged from stealth with $30 million in series A financing and a pipeline of therapies for healthy weight loss, including a dual-specific antibody targeting activin type IIA and B receptors for preservation of skeletal muscle mass.
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Antibodies attacking cancer cell
Immuno-oncology

OX40-targeting antibody displays agonistic and antitumor activity in preclinical studies

May 22, 2024
Genmab A/S, in collaboration with Biontech SE, has presented data on a novel OX40 agonist antibody –Hexabody-OX40 (GEN-1055/BNT-315), developed using Genmab’s proprietary Hexabody platform, which promotes the formation of antibody hexamers upon target binding to cell surfaces.
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Illustration of tumor in breast
Cancer

US Precision Medicine advances small-molecule drug candidate with promise for breast cancer

May 22, 2024
U.S. Precision Medicine Inc. has announced plans to use artificial intelligence (AI) technology to support work on its small-molecule drug candidate for cancer.
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Cancer

NEDD8 deficiency improves response to immune checkpoint blockade in TNBC

May 22, 2024
Researchers from Uppsala University published data from a study that aimed to reveal and validate cancer vulnerabilities to immune checkpoint blockade (ICB) therapy in triple-negative breast cancer (TNBC). A human Tumor-Immune co-Culture System (TICS), which consisted of primary human lymphocytes from healthy blood donors co-cultured with human cancer cells, was optimized to perform mechanistic investigation of clinically approved ICB drugs.
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Other news to note for May 21, 2024

May 21, 2024
Additional early-stage research and drug discovery news in brief, from: Adolore, Azitra, Fractyl Health, Gri, Reunion Neurosciences.
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Holiday notice

May 21, 2024
In accordance with the publishing schedule, BioWorld Science was not published on Monday, May 20, 2024.
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