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BioWorld - Saturday, June 20, 2026
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Ocular

Bluerock exercises option to primary photoreceptor diseases iPSC

Jan. 26, 2024
Bluerock Therapeutics LP, a wholly owned, independently operated subsidiary of Bayer AG, has exercised its option to exclusively license OpCT-001, an induced pluripotent stem cell (iPSC) derived cell therapy candidate for the treatment of primary photoreceptor diseases, from Fujifilm Cellular Dynamics Inc. and Opsis Therapeutics LLC.
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Drug Design, Drug Delivery & Technologies

Genedit and Genentech collaborate on nanoparticle delivery for nucleic acid-based medicines

Jan. 26, 2024
Genedit Inc. has entered into a multiyear collaboration and license agreement with Genentech Inc., a member of the Roche Group, to use Genedit's Nanogalaxy platform to discover and develop novel hydrophilic nanoparticles to deliver Genentech's nucleic acid-based medicines for treatment of autoimmune disease.
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Cancer

FBXW7 suppresses TNBC tumorigenesis in vivo

Jan. 26, 2024
Triple-negative breast cancer (TNBC) accounts for about 15% of invasive breast cancers, and due to the lack of well-established targets, TNBC has the worst prognosis among all breast cancer types.
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Sickle cell illustration
Hematologic

Encapsulated nucleic acid therapy shows promise for sickle cell disease

Jan. 26, 2024
Hemoglobinopathies affect 7% of the global population, and sickle cell disease (SCD) is a common form affecting 300,000 newborns per year.
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Cancer

ACx26-pep targets NANOG and FAK in triple-negative breast cancer

Jan. 26, 2024
Researchers from The Cleveland Clinic Foundation presented a novel targeted therapeutic peptide for the treatment of triple-negative breast cancer (TNBC).
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Neurology/Psychiatric

Biological staging system proposed for Parkinson's disease

Jan. 26, 2024
An international working group has proposed a new research framework that stages Parkinson's disease (PD) and defines it based on the disease's underlying biology, rather than on clinical symptoms.
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Illustration of enzyme wrapped around double helix
Cancer

Accent closes series C financing to advance cancer programs

Jan. 26, 2024
Accent Therapeutics Inc. has completed a $75 million series C financing to support progression of its lead programs through early clinical development.
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Respiratory

Prime Medicine receives funding to develop prime editors for cystic fibrosis

Jan. 26, 2024
The Cystic Fibrosis Foundation (CF Foundation) has agreed to provide Prime Medicine Inc. with up to $15 million to support the development of prime editors for the treatment of cystic fibrosis (CF).
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Lab glassware and scientist
Neurology/Psychiatric

Artelo’s FABP5 inhibitor relieves peripheral neuropathy

Jan. 26, 2024
Researchers from Artelo Biosciences Inc. reported on the preclinical characterization of ART-26.12.
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Discovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals
Ophthalmic

African ancestry GWAS yields glaucoma risk loci

Jan. 26, 2024
Primary open-angle glaucoma is the leading cause of blindness globally. Individuals of African ancestry have a disproportionately high risk of developing glaucoma, but genetic risk factors have been studied mainly in populations of European ancestry.
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