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BioWorld - Wednesday, January 21, 2026
Breaking News: BioWorld Science 2025 Year in ReviewBreaking News: BioWorld 2025 Year in ReviewBreaking News: BioWorld MedTech 2025 Year in ReviewBreaking News: Trump administration impacts continue to roil the life sciences sector
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Vaccine vials and syringe
Immune

Allergen-specific mRNA vaccine shows efficacy against allergy

Oct. 20, 2025
No Comments
Researchers from Cincinnati Children’s Hospital Medical Center and collaborating institutions in the U.S. have developed a novel approach using allergen-encoding mRNA encapsulated in lipid nanoparticles (LNPs) for both therapy and prevention of allergic responses.
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Immuno-oncology

ROR2 confirmed as suitable target for CAR T in hematologic, solid tumors

Oct. 20, 2025
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Researchers have demonstrated the potential of ROR2-specific CAR T cells.
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Ocular

Anti-IGF-1R ASO tested for Graves’ ophthalmopathy

Oct. 20, 2025
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A team of scientists demonstrated the potential of a new antisense oligonucleotide.
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Illustration demonstrating structure of the human eye and organization of retinal cells
Genetic/congenital

rAAV2-U1a-hELP1 rescues RGC function in familial dysautonomia

Oct. 20, 2025
No Comments
Familial dysautonomia (FD) is an autosomal recessive neurodevelopmental disorder.
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Endometriosis
Gynecology/obstetrics

Cyclana Bio raises funding to advance approach to endometriosis

Oct. 20, 2025
No Comments
Cyclana Bio Ltd. has closed a £5 million (US$6.7 million) pre-seed funding round.
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White Euro symbol on blue background
Cancer

Adcytherix raises $122M series A to develop novel ADCs

Oct. 17, 2025
By Nuala Moran
No Comments
A year and half from its inception, Adcytherix SAS has raised a €105 million (US$122 million) series A, enabling it to take the lead antibody-drug conjugate (ADC) program into clinical development next year.
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Cancer

Shenzhen Zhongge Biotechnology discovers new KIF18A inhibitors

Oct. 17, 2025
Shenzhen Zhongge Biotechnology Co. Ltd. has described kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Cancer

New TEAD inhibitors disclosed in Insilico Medicine patent

Oct. 17, 2025
Insilico Medicine Ltd. has divulged transcriptional enhancer factor (TEAD) inhibitors reported to be useful for the treatment of cancer and fibrosis.
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Endocrine/metabolic

Genescience Pharmaceuticals describes new PAH stabilizers for PKU

Oct. 17, 2025
Genescience Pharmaceuticals Co. Ltd. has identified phenylalanine hydroxylase (PAH) (R408W mutant) stabilizers reported to be useful for the treatment of phenylketonuria (PKU).
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Gastrointestinal

Salubris Pharmaceuticals divulges new MIR124 activators

Oct. 17, 2025
Shenzhen Salubris Pharmaceuticals Co. Ltd. has synthesized compounds acting as MIR124 activators reported to be useful for the treatment of inflammatory bowel disease and inflammatory disorders.
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