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BioWorld - Thursday, January 22, 2026
Home » Topics » Science » Biomarkers

Biomarkers
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Heart and DNA
Biomarkers

PTX3 as novel diagnostic and prognostic biomarker in myocarditis

Sep. 5, 2022
Researchers presented data from a study that aimed to evaluate pentraxin-3 (PTX3) as a circulating marker of inflammation in patients with suspected myocarditis.
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DNA illustration
SSIEM 2022

COX11 variants behind infantile-onset mitochondrial encephalopathy

Sep. 5, 2022

Mitochondrial disorders have shown phenotypic and genetic heterogeneity; cytochrome c oxidase assembly protein COX11 is an assembly factor that works as a copper chaperone. Previous findings have unveiled that COX11 knockdown causes a reduction in ATP production in vitro.


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Artery and plaque
ESC Congress 2022

Plasma COL1A1 shown to predict coronary heart disease

Sep. 2, 2022
Collagens, and in particular type I collagen, are the most abundant extracellular matrix (ECM) proteins in atherosclerotic plaques.
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2022 International Myeloma Workshop

New biomarkers of treatment resistance identified in multiple myeloma

Sep. 2, 2022
There is still a percentage of patients with multiple myeloma (MM) who do not respond to initial therapy, and they are considered as refractory MM patients. There is a need for novel biomarkers of treatment response in refractory MM.
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Blue heart and data grid
ESC Congress 2022

Plasma miR-451a is a predictor of atrial fibrillation after pulmonary vein ablation

Sep. 1, 2022
Atrial fibrillation (AF) is a very common diagnosed arrhythmia and catheter ablation is an effective treatment, but recurrence occurs after catheter ablation and remains a medical challenge. MicroRNAs can be easily detected in the circulation, and they are epigenetic regulators in many biological processes; their usefulness as biomarkers of risk stratification in patients with AF was investigated.
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ESC Congress 2022

GRP78 serum levels predict mortality in patients with coronary artery disease

Sep. 1, 2022
Researchers from University Hospital Bonn presented data from a study that aimed to evaluate the significance of serum levels of the endoplasmic-reticulum-stress chaperone GRP78 in patients undergoing coronary angiography for suspected coronary artery disease (CAD).
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Multiple myeloma illustration
2022 International Myeloma Workshop

Circulating miR-27b-3p may aid in the diagnosis and prognosis of multiple myeloma

Sep. 1, 2022
The crosstalk between immune cells and multiple myeloma (MM) cells is an important determinant of MM progression, but the mechanisms behind this have not been fully defined.
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Vascular system
ESC Congress 2022

Anti-CCP antibodies behind the progression of aortic stenosis

Sep. 1, 2022
There is a lack of biomarkers for disease activity in aortic stenosis (AS). On the other hand, citrullination is involved in many chronic inflammatory processes and citrullinated proteins have been found within atherosclerotic plaque.
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Neurology/Psychiatric

Target ALS and ADDF award grants to support biomarker research for neurodegenerative diseases

Aug. 31, 2022
Target ALS Foundation Inc. and the Alzheimer's Drug Discovery Foundation LLC (ADDF) have announced the first four award recipients in a new initiative to identify and develop biomarkers for neurodegenerative diseases, including Alzheimer's disease, amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD).
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Biomarkers

CSMD1 expression is linked to poor prognosis in patients with glioma

Aug. 30, 2022
The prognostic role of complement inhibitor CSMD1 was assessed in 1,507 patients with glioma from three different datasets. Results of the bioinformatical analysis suggested that high expression of CSMD1 was associated with increased overall survival and disease-free survival, as well as lower tumor grade.
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