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BioWorld - Friday, May 22, 2026
Home » Topics » A closer look

A closer look
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Hantavirus cells

Tracking hantavirus across the globe

May 13, 2026
No Comments
The recent hantavirus outbreak aboard the MV Hondius cruise ship has brought increased attention to an infection for which there are no widely available or FDA-approved therapeutics or vaccines, with limited research occurring only at the earliest stages. The rare Andes strain identified in the outbreak is known for human-to-human transmission, although the original infection comes from rodents. While hantavirus does not spread as easily as an infection like COVID-19, the mortality rate, at 30% to 40%, is significantly greater, and serves as another example as to why biopharmas must be at least two steps ahead with technology that can pivot to quickly address the spread of infectious diseases. Read BioWorld’s ongoing coverage of the current hantavirus outbreak.
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Close up of bow of cruise ship
Infection

Hantavirus is ‘sentinel’ more than acute pandemic threat

May 8, 2026
By Anette Breindl
No Comments
News of eight infections and three deaths so far due to an emerging zoonotic virus has brought back unhappy memories of the early days of SARS-CoV-2. At a press conference on Thursday, officials from the WHO did their best to calm the public’s fears that the MV Hondius, the ship currently heading to the Canary Islands with its remaining passengers plus assorted medical, WHO and European Center for Disease Prevention and Control staff, is the 2026 version of the Diamond Princess.
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Pink and blue neon arrows demonstrating acceleration
Gastrointestinal

Novel method BOOSTs organ growth after transplantation

April 28, 2026
By Coia Dulsat
No Comments
A major challenge in tissue engineering is not only achieving the correct cellular organization of an engineered tissue, but also expanding it to a clinically useful size after implantation. Researchers from the Wyss Institute at Harvard University have developed a synthetic biology platform that genetically programs tissues to grow large organ implants on demand. Building on a 2017 study suggesting engineered liver tissues could respond to regenerative signals released after injury, the researchers set out to identify and harness those cues.

“If we could figure out what those signals were, we could synthetically drive these factors locally in an implant to control its growth ourselves,” first author Amy Stoddard told BioWorld. Stoddard is a postdoctoral researcher at the Wyss Institute.
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Green arrow on blue abstract background

Psychedelic space expanding on Trump’s EO

April 20, 2026
By Mari Serebrov
No Comments
Timothy Leary is dead, but he could be on the outside looking in with a smile on his face as U.S. President Donald Trump’s latest executive order (EO) fuels a surge in investment in companies researching and developing psychedelic drugs to treat mental health issues. The EO, Accelerating medical treatments for serious mental illness, is intended to address the increasing burden of suicide and serious mental illness, which impacts more than 14 million Americans.
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Layered  charts
Med-tech financings Q1 2026

Med-tech financings steady at $8.8B in Q1, despite volume drop

April 16, 2026
By Amanda Lanier
No Comments
Total med-tech financings reached $8.81 billion in the first quarter (Q1) 2026, a 6% decline from $9.33 billion in Q1 2025 but well above the post-downturn lows of recent years. The 2026 total exceeds $6.45 billion in Q1 2024 and $4.69 billion in Q1 2023, indicating continued recovery from the weaker funding environment that followed the 2021 peak. While still below the $16.59 billion recorded in Q1 2019 and the pandemic-era highs, the data suggest that financing activity has stabilized at a higher baseline, with 2026 maintaining momentum despite a slight year-over-year pullback.
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Drug research illustration

Biologics in development outnumber small molecules for the first time

April 9, 2026
By Nuala Moran
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More than four decades on from the approval of the first biologic drug, the industry has reached a tipping point, and biotech drugs now outnumber small molecules in the global R&D pipeline.
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M&A cityscape
Med-tech deals Q1 2026

Blockbuster deals push med-tech M&A above $40B in Q1 2026

April 2, 2026
By Amanda Lanier
No Comments
Med-tech deal value, excluding M&As, totaled $628.41 million in the first quarter (Q1) of 2026, an increase of about 322% from the $149.08 million recorded in Q1 2025 though a 36% drop from Q4 2025‘s $978.58 million.
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Art concept for Parkinson's disease
Neurology/psychiatric

Emerging therapeutic strategies for Parkinson’s at ADPD 2026

March 23, 2026
By Mar de Miguel
No Comments
Parkinson’s disease (PD) involves the progressive loss of dopaminergic neurons, particularly in the substantia nigra. This neurodegeneration is linked to the abnormal accumulation of α-synuclein, a protein that forms toxic aggregates and spreads between cells, damaging them. At the 20th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD), held from March 17 to 21, 2026, in Copenhagen, several strategies were presented that aim to modify the course of the disease and offer real alternatives to purely symptomatic treatments.
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Arrows pointing upward
Biopharma deals February 2026

Biopharma deal value jumps 60% to start 2026

March 13, 2026
By Amanda Lanier
No Comments
Biopharma deal value reached $61.17 billion in the first two months of 2026, roughly a 60% increase from the $38.11 billion logged in the same period of 2025 and marking the strongest early year total in BioWorld’s records. The surge was driven by unusually strong activity in both months, with $31.16 billion in January and $30.01 billion in February.
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2026 outlook virtual screen, business icons.jpg

Med-tech outlook 2026: exits, financings, headwinds

March 2, 2026
No Comments
What does med tech in 2026 look like? Uncertainty remains. Global investors are confident about exit opportunities in the year ahead. But financing will be targeted. For the med-tech companies, geopolitical tensions continue to create headwinds, particularly for the European firms navigating an uncertain macroenvironment created by the reciprocal tariffs on goods entering the U.S., their primary market. By contrast, U.S. companies are bullish and believe they are well-positioned to navigate macroeconomic pressures. Still, across both regions, there is confidence in the sector and companies remain focused on advancing their technologies to address clinical needs – innovating, conducting trials, presenting data, raising funds, and delivering products that improve patients’ lives.
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