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Appointments and advancements for Dec. 18, 2024

Dec. 18, 2024
New hires and promotions in the biopharma industry, including: Adicet, Akari, Anaveon, Karolinska, Neutrolis, Noema, Valink.
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Regulatory actions for Dec. 18, 2024

Dec. 18, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Eli Lilly, Eva, Everest, Eyedna, Gilead, Jaguar, Lipocine, Merck, Merz, Tonix, Viiv.
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Financings for Dec. 18, 2024

Dec. 18, 2024
Biopharmas raising money in public or private financings, including: Akamis, Alpha Cognition, Biper, Candel, CG Oncology, Indapta, Reviva, Satellos, Xuanzhu.
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Human cell illustration
Endocrine/metabolic

Cell mapping yields clues to metabolic health in obese individuals

Dec. 18, 2024
By Anette Breindl
Researchers at the University of Leipzig and ETH Zurich have used single-cell sequencing to identify differences between fat tissue of obese individuals who are metabolically unhealthy, and those who were in good metabolic health. The findings, which were published online Dec. 17, 2024, in Cell Metabolism, identify measurements that can be used to decouple obesity from metabolic disease.
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Ozempic pen and packaging

Danish regulators question possible Ozempic link to rare eye condition

Dec. 17, 2024
By Nuala Moran
The Danish Medicines Agency is to ask the EMA’s pharmacovigilance committee to investigate a potential increased risk of an acute eye condition in diabetic patients being treated with the glucagon-like peptide-1 receptor agonist Ozempic (semaglutide).
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Freed from clinical hold, Biomea’s menin inhibitor solid in T2D

Dec. 17, 2024
By Lee Landenberger
Released from a clinical hold by the U.S. FDA in late September, Biomea Fusion Inc.’s menin inhibitor, icovamenib, has charged ahead to produce positive top-line data from a phase II study in type 2 diabetes (T2D). The data, however, didn’t stop the stock from dropping to near its lowest level of the past 12 months.
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Man measuring waist

Caliway’s CBL-514 meets endpoints in reducing abdominal fat

Dec. 17, 2024
By Tamra Sami
Caliway Biopharmaceuticals’ lipolysis candidate, CBL-514, met all the primary and secondary efficacy endpoints in a phase IIb study for subcutaneous fat reduction, paving the way for the company to begin a global pivotal phase III study in 2025.
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Radiotherapy of cancer

SK Biopharma, Proen team up to develop new radiopharmaceuticals

Dec. 17, 2024
By Marian (YoonJee) Chu
SK Biopharmaceuticals Co. Ltd. and Proen Therapeutics Co. Ltd. joined hands in a research collaboration to advance up to two preclinical small protein-based radiopharmaceuticals by 2027 – the year SK Biopharmaceuticals aims to “become a leading radiopharma player” worldwide.
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T cells

Candid, Epimab ink $1B T-cell engager deal in autoimmune disease

Dec. 17, 2024
By Tamra Sami
Candid Therapeutics Inc. and Epimab Biotherapeutics Inc. have entered a $1 billion research collaboration to discover and develop novel T-cell engager candidates for autoimmune indications.
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Kyorin in-licenses Bayer’s phase II sleep apnea drug for €85M+

Dec. 17, 2024
By Tamra Sami
Kyorin Pharmaceutical Co. Ltd. has acquired Bayer AG’s phase II obstructive sleep apnea candidate, BAY-2925976, in a deal worth €85M (US$89.3 million) plus sales-based royalties and commercial milestones.
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