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BioWorld - Tuesday, July 14, 2026
Home » Alzheimer’s disease

Articles Tagged with ''Alzheimer’s disease''

Neurons with dendrites affected by amyloid plaques in Alzheimer's disease

Fujirebio Alzheimer’s test wins first FDA clearance

May 20, 2025
By Annette Boyle
Fujirebio Diagnostics Inc.’s Alzheimer’s disease assay received the U.S. FDA’s first clearance for a blood test for the debilitating neurodegenerative disease. Fujirebio’s Lumipulse G pTau217/ß-Amyloid 1-42 plasma ratio is indicated for the early detection of amyloid plaques associated with Alzheimer’s disease in symptomatic individuals aged 55 years and older.
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Neurons with dendrites affected by amyloid plaques in Alzheimer's disease

Fujirebio Alzheimer’s test wins first FDA clearance

May 19, 2025
By Annette Boyle
Fujirebio Diagnostics Inc.’s Alzheimer’s disease assay received the U.S. FDA’s first clearance for a blood test for the debilitating neurodegenerative disease. Fujirebio’s Lumipulse G pTau217/ß-Amyloid 1-42 plasma ratio is indicated for the early detection of amyloid plaques associated with Alzheimer’s disease in symptomatic individuals aged 55 years and older.
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Therini Bio locks in another $39M for its fibrin-targeting immunotherapies

May 16, 2025
By Brian Orelli
No Comments
Therini Bio raised an additional $39 million in its series A financing round, bringing the total for the round to $75 million. The capital will be used to advance its fibrin-targeting immunotherapies for neurodegenerative diseases.
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voinosis
Patents

Voinosis uses AI and voice analytics for early dementia diagnosis

April 30, 2025
By Simon Kerton
Seoul, South Korea-based Voinosis Co. Ltd. filed for potential worldwide protection of its AI-based system that allows for the early detection cognitive impairment, dementia, Alzheimer’s disease and hearing loss through voice analysis.
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Researcher looking through a microscope
Neurology/psychiatric

Preclinical validation of [11C]KIn-83 PET tracer

April 23, 2025
α7 nicotinic acetylcholine receptors (α7nAChRs), expressed in neurons and astrocytes at lower levels, have been implicated in neuroinflammatory and neurodegenerative processes associated with Alzheimer’s disease (AD). Evidence suggests that α7nAChRs interact with soluble amyloid-β (Aβ), contributing to reactive astrogliosis and formation of Aβ plaques in AD.
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Man piecing together a puzzle
Neurology/psychiatric

Discovery and preclinical results of a Rac1 inhibitor for Alzheimer’s

April 17, 2025
At the 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders (ADPD), researchers from Beijing Joekai Biotechnology LLC presented the discovery process and preclinical results for 50561.
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Neurology/psychiatric

Alzheimer’s vaccine selectively targets toxic amyloid-β oligomers

April 17, 2025
Promis Neurosciences Inc. recently presented the rational design of an Alzheimer’s disease (AD) vaccine candidate maximizing the selective targeting of toxic amyloid-β oligomers.
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Neurology/psychiatric

Preclinical profile of LY-3954065, a pioneering siRNA for Alzheimer’s disease

April 16, 2025
Researchers from Eli Lilly & Co. reported preclinical data on LY-3954068, a MAPT small-interference RNA (siRNA) strategy in AD models. The therapy is designed to reduce tau protein synthesis by inhibiting the translation of MAPT mRNA, with the goal of effectively lowering all forms of tau.
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Neurology/psychiatric

PTG-630 improves cognitive deficits in Alzheimer’s mouse models

April 15, 2025
Praetego Inc. and University of California San Diego scientists reported preclinical results for the new small-molecule amadorin PTG-630, a brain-penetrant drug candidate that inhibits the formation of advanced glycation end-products (AGEs).
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Illustration of head with maze that is missing parts
Neurology/psychiatric

Neurizon’s NUZ-001 confers neuroprotection in preclinical neurodegeneration models

April 14, 2025
Neurizon Therapeutics Ltd. has presented preclinical data on their compound NUZ-001 for the potential treatment of neurological disorders.
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