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BioWorld - Monday, December 29, 2025
Home » Alzheimer’s disease

Articles Tagged with ''Alzheimer’s disease''

Neurons with dendrites affected by amyloid plaques in Alzheimer's disease
JPM Healthcare Conference

Sunbird Bio soars into neurodegenerative diagnostic space

Jan. 14, 2025
By Holland Johnson
As 2025 makes its debut, one of the topics gaining momentum in health care is the diagnosis and potential treatment of neurodegenerative diseases, a scourge that threatens to overwhelm society and drain treatment budgets around the world. One company looking to find solutions to the oncoming neurodegenerative disease tsunami is privately held Sunbird Bio Inc., which is developing blood-based diagnostic platform for neurological diseases like Alzheimer’s and Parkinson’s disease.
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Neurology/psychiatric

Discovery of novel antioxidant and metal-chelating agent with neuroprotective activity

Jan. 14, 2025
Scientists at Universidade Federal Rural do Rio de Janeiro (UFRRJ) have reported a novel multitarget-directed ligand (MTDL) targeting butyrylcholinesterase (BChE) with potential for development as an antioxidant and metal-chelating agent for the treatment of Alzheimer’s disease.
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Tau neuron illustration
Diagnostics

[18F]FA1, a tau-PET radiotracer with excellent affinity and selectivity

Jan. 13, 2025
Work at Beijing Normal University and affiliated organizations has led to the discovery and preclinical characterization of a novel tau-PET radiotracer for Alzheimer’s disease (AD).
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Hands holding brain
Neurology/psychiatric

Novel NLRP3 inhibitor shows neuroprotective effect

Jan. 8, 2025
Neuroinflammation is a key feature of Alzheimer’s disease (AD). The activation of the NLRP3 inflammasome has been associated with the pathogenesis of AD, therefore, targeting NLRP3 may help reduce neuroinflammation and slow down the progression of AD.
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Elderly hands holding broken brain structure
Neurology/psychiatric

Zhongzhi drops $3M in Gabaeron series A for stem cell AD therapy

Jan. 3, 2025
By Marian (YoonJee) Chu
Zhongzhi Pharmaceutical Holdings Ltd. made a $3 million investment in a series A financing round of stem cell therapy developer Gabaeron Inc. Dec. 21, expected to help propel Gabaeron’s preclinical Alzheimer’s disease (AD) candidate into phase I testing.
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Elderly hands holding broken brain structure

Zhongzhi drops $3M in Gabaeron series A for stem cell AD therapy

Dec. 31, 2024
By Marian (YoonJee) Chu
Zhongzhi Pharmaceutical Holdings Ltd. made a $3 million investment in a series A financing round of stem cell therapy developer Gabaeron Inc. Dec. 21, expected to help propel Gabaeron’s preclinical Alzheimer’s disease (AD) candidate into phase I testing.
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Elderly woman holding illustration of brain with missing puzzle piece
Neurology/psychiatric

New M1 orthosteric agonist protects against scopolamine-induced damage in in vitro Alzheimer’s disease model

Dec. 27, 2024

Defects in the cholinergic signaling pathway have been shown to underlie Alzheimer’s disease and its symptoms. 


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Bioarctic, Bristol Myers join efforts in $1.35B Alzheimer’s deal

Dec. 23, 2024
By Karen Carey
In a deal worth $100 million up front and up to $1.25 billion in milestone payments, Bioarctic AB licensed its pyroglutamate-amyloid-β (pyroglutamate-Aβ) antibody program to Bristol Myers Squibb Co. to advance treatments for Alzheimer’s disease.
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Bioarctic, Bristol Myers join efforts in $1.35B Alzheimer’s deal

Dec. 20, 2024
By Karen Carey
In a deal worth $100 million up front and up to $1.25 billion in milestone payments, Bioarctic AB licensed its pyroglutamate-amyloid-β (pyroglutamate-Aβ) antibody program to Bristol Myers Squibb Co. to advance treatments for Alzheimer’s disease.
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Man piecing together a puzzle
Neurology/psychiatric

Bristol Myers Squibb licenses Bioarctic’s Aβ antibody program

Dec. 20, 2024
Bioarctic AB has entered into a global exclusive license agreement with Bristol Myers Squibb Co. for Bioarctic’s pyroglutamate-amyloid-β (Aβ) antibody program.
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