The largest single cell transcriptomics study of neuroblastoma to date has discovered that this childhood cancer arises from a single type of embryonic cell, the sympathoblast.
Keeping you up to date on recent developments in neurology, including: Smartwatch sensors enable remote monitoring, treatment guidance for Parkinson’s patients; Imaging of a living brain can help differentiate dementia; Morphine itch comes from neurons, not mast cells.
Keeping you up to date on recent developments in diagnostics, including: A deep learning tool to predict cardiovascular risk; Smartphone-based COVID-19 test; PCOS passed on in the epigenes.
KRAS is the most frequently mutated oncogene in solid tumors in general, and in lung tumors in particular. There are more patients whose lung tumors are driven by KRAS mutations than by ALK, Ros, Ret and TRK alterations. Combined. And after 40 years, they look to be getting a targeted therapy, or even two.
A Singapore study led by the Novartis Institute for Tropical Diseases (NITD) has shown that a novel small-molecule inhibitor of the dengue virus (DENV) nonstructural protein 4B (NS4B) has favorable pharmacokinetics and efficacy in preclinical animal models, the authors reported in the February 3, 2021, edition of ScienceTranslationalMedicine.
Keeping you up to date on recent developments in orthopedics, including: Blood pressure can be controlled without drugs after spinal cord injury; Researchers develop technique to replicate bone-remodeling processes; New technique to fast-track pain research.
Spatially resolved transcriptomics, which Nature Methods named as its Method of the Year for 2020, allows researchers to look at transcriptional activity while preserving the spatial relationship of different transcripts.
KRAS is the most frequently mutated oncogene in solid tumors in general, and in lung tumors in particular. There are more patients whose lung tumors are driven by KRAS mutations than by ALK, Ros, Ret and TRK alterations. Combined.
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