Investigators at the University of Heidelberg have identified a previously unknown mechanism for excitotoxicity and used their insight to identify “unconventional neuroprotectant” compounds that could prevent cell death and reduce brain damage in a mouse model of stroke.
A multi-institutional team of researchers has discovered that acute lymphoblastic leukemia cells metabolically adapt to the cerebrospinal fluid-filled CNS microenvironment upon migration from the bone marrow with alterations in fatty acid synthetic pathways.
Keeping you up to date on recent developments in diagnostics, including: Improving sensitivity of COVID-19 tests; Deep learning algorithm helps triage suspected COVID-19 cases; Cancer image analysis tool incorporates HER2 biomarker assay.
Keeping you up to date on recent developments in orthopedics, including: LED-based UV irradiation safely prevents the loss of bone and muscle mass in mice; Coupling antibiotics with stem cells to fight off bone infections; Study: Unnecessary stress testing performed prior to knee and hip replacement surgeries.
Surprising no one, Jennifer Doudna and Emmanuelle Charpentier won the 2020 Nobel Prize in Chemistry “for the development of a method for genome editing,” that is, the CRISPR/Cas9 system.
A whole-genome clustered regularly interspaced short palindromic repeats (CRISPR) screening study is the first to identify the gene regulating the inflammatory response and immune cell death during sepsis, Australian researchers reported in the October 5, 2020, edition of Nature Immunology.
Keeping you up to date on recent developments in oncology, including: New data cast doubt on post-resection radiotherapy for NSCLC; Carcinogens need not be mutagens; Myelin regulatory factor assists pancreatic cancer cells; Deepmedic provides glioblastoma segmentation with sparsified data.
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