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BioWorld MedTech’s Orthopedics Extra for Jan. 6, 2021

Jan. 6, 2021
By Liz Hollis
Keeping you up to date on recent developments in orthopedics, including: Discovery of aging mechanism for hematopoietic stem cells; Long-term study finds dozens of new genetic markers associated with lifetime bone growth; Living alone may increase risk of dying after hip fracture; Bone fracture risk may increase when critical enzymatic processes decline.
Read More
Cryo-EM structure

Penciling in the right base corrects progeria mutation

Jan. 6, 2021
By Anette Breindl
Using an adenine base editor, researchers at the U.S. NIH, Vanderbilt University Medical Center and Harvard University have succeeded in treating the premature aging syndrome Hutchinson-Guilford progeria syndrome (progeria) in mice, extending the animals’ lifespan and preventing much of the vascular damage that is typically the cause of death in children with progeria.
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Coronavirus mutation illustration
Mask up

COVID anniversary coincides with advent of more transmissible variants

Jan. 5, 2021
By Anette Breindl
It has been a year since Wuhan health authorities first issued a bulletin about a cluster of pneumonia cases of unknown cause, first bringing what would become the COVID-19 pandemic to the attention of the World Health Organization. Now, a mutation that significantly increases SARS-CoV-2’s transmissibility has been detected in the U.S. 
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BioWorld MedTech’s Oncology Extra for Jan. 5, 2021

Jan. 5, 2021
By Mark McCarty
Keeping you up to date on recent developments in oncology, including: Cellular ‘backpack’ boosts activity of macrophages against cancer; Hardware + software = slide-free histology; Researchers wary of social media for clinical trial recruitment; Peptides team up with nanowires to detect cancer exosomes.
Read More
Human NK cell
Bench Press

Activating NK cells without interleukins

Jan. 5, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: ApoE multitasks for regulating brain lipids.
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Gloved hand holding petri dish in lab

Protein introns, "inteins", are antifungal targets

Jan. 5, 2021
By Anette Breindl
Researchers from the State University of New York at Albany have identified small molecules that could inhibit intein self-splicing from the protein PrP8 in the fungal pathogens Cryptococcus neoformans and Cryptococcus gattii, emerging pathogens that can cause fungal meningitis in immunocompromised patients.
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BioWorld MedTech’s Cardiology Extra for Jan. 4, 2021

Jan. 4, 2021
By Liz Hollis
Keeping you up to date on recent developments in cardiology, including: Researchers outline new stroke strategy; Group assesses role of neutrophil extracellular traps in coronary thrombosis in COVID-19 patients; Link identified between metabolic syndrome and higher cardiovascular risk in patients with psoriasis.
Read More
Mycobacterium tuberculosis
Bench Press

Killing Mycobacterium tuberculosis, some assembly required

Jan. 4, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Liver metastases are immunosuppressive.
Read More
Stomach and intestine

B-cell transcription factor helps gut regenerate

Jan. 4, 2021
By John Fox
A Chinese study has shown that the recently discovered transcription factor Bach2, which is important in B-cell development and progression of inflammatory disease, also regulates gastrointestinal regeneration by facilitating DNA repair after ionizing radiation exposure.
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BioWorld MedTech’s Diagnostics Extra for Dec. 31, 2020

Dec. 31, 2020
By Meg Bryant
Keeping you up to date on recent developments in diagnostics, including: Arterial stiffness and mental decline; Wearables can help to predict COVID-19; Putting patients in control of type 2 diabetes with smart choices, CGMs.
Read More
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