Two recent studies have independently identified macropinocytosis, a nutrient procurement pathway whereby cancer cells take up extracellular fluid droplets containing proteins and other macromolecules, as a promising new therapeutic target for pancreatic ductal adenocarcinoma (PDAC).
A large-scale metabolomics study of blood samples from 11,000 people has identified common biological links among a number of chronic non-communicable diseases, opening up the possibility of countering multiple diseases simultaneously.
Keeping you up to date on recent developments in neurology, including: Using AI to track facial changes due to Parkinson’s; Dopamine plays role in pain perception sex differences; Lipid dysregulation gives information on Parkinson’s.
Pre-existing insulin-secreting pancreatic beta cells, but not their progenitors, have been shown to contribute to new beta cells in the adult pancreas, according to a Chinese study led by scientists at the Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences.
Keeping you up to date on recent developments in diagnostics, including: Data flaws sink current AI models for COVID-19 diagnosis; Smartphone-based gaze may provide a scalable, digital biomarker of mental fatigue; AI developed to predict disease based on genetic mutations; High blood fats, sugars alter antigen processing.
Keeping you up to date on recent developments in orthopedics, including: Examining the value of lumbar spine surgery; Hip fracture outcomes worse during busy periods; Predicting the likelihood of bone fractures in older men.
LONDON – The alchemy of induced pluripotent cells has broken another barrier, delivering a model of the earliest preimplantation stages of human development, when fertilized eggs form a blastocyst.