Taiwanese researchers have elucidated the signaling mechanism downstream of IL-17 receptor B and shown that its blockade using a neutralizing antibody reduced pancreatic cancer tumorigenesis and metastasis, while prolonging the life of tumor-bearing mice.
Keeping you up to date on recent developments in cardiology, including: TAVR patients at low surgical risk still ahead vs. SAVR, but thrombosis a concern; Heart failure numbers nearly doubled between 1990 and 2017; COVID exerting large effect on heart health.
A study led by scientists at Osaka University Graduate School of Medicine has identified the previously unknown molecular mechanism underlying bone marrow regeneration after chemotherapy, which damages hematopoietic stem and progenitor cells.
Keeping you up to date on recent developments in neurology, including: AI reveals drugs that may be repurposed for Alzheimer’s disease; Treating Parkinson’s disease symptoms with brain cell grafts; Astrocytes are more inflammatory in bipolar disease; Pain on the brain.
DUBLIN – A novel real-world study methodology that marries digital technology with a citizen science or do-it-yourself approach to “drug” procurement, formulation and administration has found – yet again – that the placebo remains one of the great wonders of the medical world.
Keeping you up to date on recent developments in diagnostics, including: Rapid POC test for respiratory infections may reduce antibiotic use; Risk-stratification tools help conserve ventilator, ICU bed use; Diverse populations, long reads give genome insights; Neurons contribute to their own lack of regeneration.
At the 2021 Advances in Genome Biology and Technology meeting, John Greally had some unusual advice with respect to confounders in epigenomic studies. Epigenomics, he told the audience in his talk on "Thinking beyond the creode: epigenomics and human disease," has real promise for understanding genomic mechanisms of disease. "But possibly not in the way we think."
Keeping you up to date on recent developments in orthopedics, including: Treating rheumatoid arthritis with micromotors; Bioengineered hybrid muscle fiber for regenerative medicine; Immunosuppressive cell and cytokine response linked to bone nonunion.
"Nothing is undruggable!" was the bold claim at the European Society of Medical Oncology Targeted Anticancer Therapies Virtual Congress 2021 the (ESMO-TAT).
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