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Home » Topics » Science

Science
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Elderly hands holding broken brain structure

Alzheimer's disease subtypes may explain, improve clinical results

Jan. 14, 2021
By Anette Breindl
Alzheimer’s disease can be divided into multiple subtypes based on gene expression patterns, investigators at the Mount Sinai School of Medicine reported in the Jan. 6, 2021, issue of Science Advances. The work, corresponding author Bin Zhang told BioWorld, is “the first major finding of subtypes in Alzheimer’s disease.”
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RNA
Bench Press

Mis-spliced RNAs in tumor cells trigger antiviral response

Jan. 14, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Cellular underpinnings of allergen immunotherapy success.
Read More

BioWorld MedTech’s Orthopedics Extra for Jan. 13, 2021

Jan. 13, 2021
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: New treatment allows some people with spinal cord injury to regain hand and arm function; Scientists reveal how gut microbes can influence bone strength in mice; New drug form may help treat osteoporosis, calcium-related disorders; Hip fracture incidence expected to increase substantially in some Eurasian countries.
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Stem cells
Bench Press

Presenilin mutations affect neuronal stem cells

Jan. 13, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: New causal gene for chronic kidney disease; New classification scheme for glioblastomas.
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BioWorld MedTech’s Oncology Extra for Jan. 12, 2021

Jan. 12, 2021
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Study delineates four cell states in glioblastoma; CARs with switches; Activating NK cells without interleukins; Liver metastases are immunosuppressive.
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Hands holding petri dish

Antibody protects broadly against flaviviruses, without ADE

Jan. 12, 2021
By John Fox
A study led by Australian researchers at the University of Queensland has shown that a newly developed antibody targets the flavivirus nonstructural protein 1 and was shown to reduce viremia and improve survival in mouse models of dengue, Zika and West Nile infections.
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Red blood cells
Bench Press

‘Unconventional’ γδ T cells recognize malaria-infected RBCs

Jan. 12, 2021
By Anette Breindl
BioWorld looks at translational medicine.
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BioWorld MedTech’s Cardiology Extra for Jan. 11, 2021

Jan. 11, 2021
By Liz Hollis
Keeping you up to date on recent developments in cardiology, including: MRI shows lower degrees of myocarditis in athletes who have recovered from COVID-19; Nanodroplets, ultrasound drills show promise with blood clots; Common blood pressure meds safe for those with COVID-19.
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Antibody

Antibodies target fibrotic and autoimmune diseases

Jan. 11, 2021
By John Fox
A Sino-U.S. study has shown that the increased expression of the small secreted glycoprotein follistatin-like 1 is critical in the pathogenesis of multiple fibrotic and systemic autoimmune diseases, the authors reported in the January 6, 2021, print edition of Molecular Therapy after earlier publication online.
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BioWorld MedTech’s Neurology Extra for Jan. 8, 2021

Jan. 8, 2021
By Andrea Applegate
Keeping you up to date on recent developments in neurology, including: Focused ultrasound shows promise for Parkinson’s disease; Blood test developed for Alzheimer’s prognosis in symptom-free patients; Bedside EEG test predicts recovery in unresponsive brain injury patients.
Read More
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