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BioWorld - Thursday, March 30, 2023
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Brain, illustrating pain/injury

Brain injury modulates bone marrow cells to reduce neuroinflammation

April 19, 2021
By John Fox
No Comments
Chinese neuroscientists have identified a bone marrow (BM) response to acute brain injury, in which the fate and function of BM hematopoietic cells are shaped by brain injury, suggesting that the brain can mobilize a population of protective monocytes and direct them to the injury site.
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Digital cancer cells illustration

New target identified for treatment-resistant CRC

April 16, 2021
By Nuala Moran
No Comments
Organoids cultured from patient-derived colorectal cancer cells have been used to demonstrate for the first time that tumors which have developed resistance to the full range of existing treatments, across chemotherapies, targeted therapies and immunotherapies, retain a requirement for Werner helicase (WRN) for survival. WRN has a key role in the maintenance of genome stability, but although loss of WRN is known to initiate synthetic lethality in DNA mismatch repair deficient colorectal cancer, studies into the effect of inhibiting that helicase have to date been limited to a handful of cell lines.
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BioWorld MedTech’s Neurology Extra for April 16, 2021

April 16, 2021
By Andrea Applegate
No Comments
Keeping you up to date on recent developments in neurology, including: How tangled proteins kill brain cells, promote Alzheimer’s; Studies evaluate use of telemedicine with Cala Trio; Autism develops differently in girls than boys, new research suggests.
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Test tube, dropper, DNA illustration

Aussie researchers show critical role of DC-SCRIPT in producing key dendritic immune cell

April 16, 2021
By Tamra Sami
No Comments
Australian researchers have discovered a key differentiation process that provides an essential immune function in helping to control cancer and infectious diseases.
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Microscope and coronavirus illustration

New Oxford analysis uncovers brain clotting risk due to COVID-19 infection

April 15, 2021
By Cormac Sheridan
No Comments
DUBLIN – A newly published retrospective analysis of the electronic health care records of more than 500,000 COVID-19 patients has found that infection with SARS-CoV-2 carries “a significantly and substantially” greater risk of cerebral venous thrombosis (CVT) than does either one of the two approved mRNA COVID-19 vaccines or infection with influenza virus.
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BioWorld MedTech’s Diagnostics Extra for April 15, 2021

April 15, 2021
By Meg Bryant
No Comments
Keeping you up to date on recent developments in diagnostics, including: Imbalance in gum bacteria linked to Alzheimer-related protein in healthy adults; Tiny device monitors deep-tissue oxygen.
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Digital cancer cells illustration

New target identified for treatment-resistant CRC

April 14, 2021
By Nuala Moran
No Comments
Organoids cultured from patient-derived colorectal cancer cells have been used to demonstrate for the first time that tumors which have developed resistance to the full range of existing treatments, across chemotherapies, targeted therapies and immunotherapies, retain a requirement for Werner helicase (WRN) for survival.
Read More

BioWorld MedTech’s Orthopedics Extra for April 14, 2021

April 14, 2021
By Holland Johnson
No Comments
Keeping you up to date on recent developments in orthopedics, including: X-rays confirm promise of new luminescent markers; Pillar of support: Breakthrough discovery could speed up bone implant recovery; New biosealant can stabilize cartilage, promote healing after injury.
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Stomach and intestine

New agonist MAb resolves chronic inflammation

April 14, 2021
By John Fox
No Comments
A French study has demonstrated that the novel agonist anti-human ChemR23 monoclonal antibody (MAb) designated OSE-230 accelerated recovery from acute inflammation and triggered resolution of chronic inflammation in mice chronic colitis models, preventing fibrosis and reducing tumor development.
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BioWorld MedTech’s Oncology Extra for April 13, 2021

April 13, 2021
By Mark McCarty
No Comments
Keeping you up to date on recent developments in oncology, including: NIH drug screening protocol identifies treatment for SCLC; Explanation for DR5 antibody problem surfaces; Location, location, location in avoidance of esophagitis.
Read More
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