LONDON – The genomes of 38 different tumor types and the 47 million mutations that fostered their growth are revealed in unprecedented detail in 23 studies published in Nature and other journals on Feb. 6, 2020.
Keeping you up to date on recent developments in orthopedics, including: After a bone injury, shape-shifting cells rush to the rescue; Machine-learning tool identified predictive factors associated with worse patient outcomes after arthroscopic hip surgery; New injection technique may boost spinal cord injury repair efforts; Does tramadol increase hip fracture risk?
At this very early point in the emerging 2019-nCoV outbreak, knowledge about the virus is insufficient to predict what shape that outbreak will ultimately take. But knowledge about the virus is accumulating at remarkable speed, and experience with other viruses is helping to shape the response to the newest coronavirus threat. 2019-nCoV, sometimes called Wuhan coronavirus after its source, is the third coronavirus after SARS-CoV and MERS-CoV with the potential to cause serious illness and death that has emerged since the beginning of the 21st century.
Keeping you up to date on recent developments in oncology, including: New algorithm can distinguish between subtypes in low-grade glioma; Different drivers can turn the wheel in glioblastoma’s vicious cycle; Commercial antibodies underwhelm for studies of PP2A; Foundation awards more than $1M for cancer research; Protons better for sparing cognitive function in pediatric patients.
Keeping you up to date on recent developments in cardiology, including: Long QT genes mostly short on evidence; Cerebrospinal fluid is early culprit in stroke edema; Regenerative HBOT protocols appear to improve cardiac function in healthy aging heart population; Blood test IDs risk of disease linked to stroke, dementia.
BioWorld looks at translational medicine, including: Adapting NGS for coronavirus surveillance; Long QT genes mostly short on evidence; Reservoir dogs don’t hunt; Another reason to get a flu shot; Cerebrospinal fluid is early culprit in stroke edema; Different drivers can turn the wheel in glioblastoma’s vicious cycle; From African genomes, big insights with small sample size; Commercial antibodies underwhelm for studies of PP2A; Tau keeps gliomas in check.
Keeping you up to date on recent developments in neurology, including: Improving memory with noninvasive electrostimulation successfully studied in mice; AI analysis can predict progression of neurodegenerative disease from blood test; Study finds that after stroke, brain drowns in its own fluid; Immune response in brain, spinal cord could offer clues to treating neurological diseases.
DUBLIN – The witty Twitter account @justsaysinmice, run by Northeastern University research scientist Jim Heathers, offers a very useful corrective to the misleading and unwarranted hype that often accompanies preclinical studies in mice. What looks good in murine models is all too often lost in translation, for a whole host of reasons, and never has any useful effect in patients. That’s not a concern for a group led by Thomas Thum, of the Institute of Molecular and Translational Therapeutic Strategies at Hannover Medical School in Germany, who just published in Nature Communications the outcome of what is probably the largest ever pig study in heart failure.
Keeping you up to date on recent developments in diagnostics, including: Increasing early disease detection; Adapting NGS for coronavirus surveillance; AD and HHV: Still a mystery; Increasing accuracy of malaria diagnoses
When developmental neurobiologist Arnold Kriegstein talks about his work, it sounds for all the world like he is talking about the brains of teenagers. They are stressed. Their identity is mixed up. But putting them in a good environment is helpful to their development. Kriegstein, though, was describing brain organoids.