Aging, which is associated with various pathologies such atherosclerosis and cancer, is characterized by an accumulation of senescent cells. Cellular senescence blocks cell proliferation, but it decreases the health of the old by littering tissues with dysfunctional senescent cells.
Keeping you up to date on recent developments in diagnostics, including: Improving diagnosis of brain diseases; Predicting survival of COVID-19 patients; New causal gene for chronic kidney disease.
Alzheimer’s disease can be divided into multiple subtypes based on gene expression patterns, investigators at the Mount Sinai School of Medicine reported in the Jan. 6, 2021, issue of Science Advances. The work, corresponding author Bin Zhang told BioWorld, is “the first major finding of subtypes in Alzheimer’s disease.”
Keeping you up to date on recent developments in orthopedics, including: New treatment allows some people with spinal cord injury to regain hand and arm function; Scientists reveal how gut microbes can influence bone strength in mice; New drug form may help treat osteoporosis, calcium-related disorders; Hip fracture incidence expected to increase substantially in some Eurasian countries.
Keeping you up to date on recent developments in oncology, including: Study delineates four cell states in glioblastoma; CARs with switches; Activating NK cells without interleukins; Liver metastases are immunosuppressive.
A study led by Australian researchers at the University of Queensland has shown that a newly developed antibody targets the flavivirus nonstructural protein 1 and was shown to reduce viremia and improve survival in mouse models of dengue, Zika and West Nile infections.
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