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BioWorld - Sunday, March 15, 2026
Home » Topics » Clinical

Clinical
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Tearcare system components

Sight Sciences highlights positive results from Tearcare

May 18, 2020
By Liz Hollis
Dry eye disease is a common problem, and Sight Sciences Inc., of Menlo Park, Calif., is looking to help those who suffer from the condition. Now, the company has seen the presentation of positive clinical data from the multicenter OLYMPIA study of Tearcare, which the company has heralded as the first wearable and intelligent eyelid technology for dry eye treatment.
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Aerobox in use with patient

Refrigerator cabinets turned into medical devices to fight COVID-19

May 18, 2020
By Sergio Held
BOGOTA – Mexican home appliances manufacturer Mabe Sa De Cv, from Mexico City, became a new member of the med-tech sector after taking the leap forward and joining the scores of companies around the world shifting their traditional manufacturing lines to develop med-tech products to fight COVID-19.
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Test of Viiv's cabotegravir stopped early on strong efficacy vs. Truvada

May 18, 2020
By Michael Fitzhugh
A global HIV prevention study comparing a long-acting injectable antiretroviral from Viiv Healthcare Ltd. to a daily pill from Gilead Sciences Inc. has stopped early after Viiv's cabotegravir proved 69% more effective than the current standard of care, Gilead's Truvada (emtricitabine/tenofovir), in preventing HIV acquisition (95% CI 41%-84%).
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Doctor and patient consultation

Clinical trials still lack diversity, FDA encouraging inclusiveness

May 18, 2020
By Brian Orelli
Women, black and Hispanic/Latinx participants were underrepresented in pivotal clinical trials for drugs approved from 2007 to 2017, according to a new report by the Tufts Center for the Study of Drug Development. In the pivotal clinical trials, 44.9% of patients were women. Participants who identified as black or of African descent were the most underrepresented participant group, representing 5.4% of participants in clinical trials.
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Syringe and ampoules

Sera smile: Moderna haulin’ oats in race for COVID-19 vaccine

May 18, 2020
By Randy Osborne
Moderna Inc.’s chief medical officer, Tal Zaks, said that the results in hand “give us great confidence that we've got the right dose range for phase III” work slated to begin this summer with COVID-19 vaccine prospect mRNA-1273. A regulatory filing could come as early as 2021.
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Eye drops

Oculis hits endpoints in phase IIb trial of OCS-01 in cataract surgery

May 18, 2020
By Nuala Moran
LONDON – Oculis SA has delivered positive phase IIb data for OCS-01, a topical nanoparticle formulation of dexamethasone, in the treatment of the after-effects of cataract surgery, meeting the primary endpoints of reducing both inflammation and pain.
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In the clinic for May 18, 2020

May 18, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Bayer, Biogen, Biolinerx, Bone Therapeutics, Can-Fite, Chemocentryx, Cindome, Eyepoint, Heron, Janssen, JHL Biotech, Lipac, Moderna, Octapharma, Oculis, Oryzon, Progenics, Rapt, Recardio, Rezolute, Samsung Bioepis, Spark, TLC, Viiv, Zai Lab.
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Catty-wonky conclusion?

Cassava seeks flaw that sunk phase II Alzheimer’s trial

May 15, 2020
By Michael Fitzhugh
A new phase IIb readout at odds with earlier data suggesting PTI-125 would diminish key biomarkers of neuroinflammation and neurodegeneration in Alzheimer’s patients has left Cassava Biosciences Inc. President and CEO Remi Barbier looking for answers.
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In the clinic for May 15, 2020

May 15, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Amarin, Astellas, Caladrius, Cassava, Contrafect, Exicure, Ferring, Gesynta, Implicit, Merck, Mersana, Orchard, Orexo, Pfizer, Roche, Samsung, Trillium, Ultragenyx, Urogen, VBI, Venatorx.
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Allez-oop!

Allogene shares jump on early new NHL data

May 14, 2020
By Michael Fitzhugh
Shares of Allogene Therapeutics Inc. (NASDAQ:ALLO) leapt 36% higher to $42.12 on Thursday after limited data from a small number of relapsed/refractory (r/r) non-Hodgkin lymphoma patients showed a combination of the company's anti-CD19 allogeneic CAR T candidate, ALLO-501, and an anti-CD52 monoclonal antibody, ALLO-647, met with an overall response rate of 78%.
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