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BioWorld - Sunday, July 19, 2026
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Hands holding paper

Researchers hit back after colleagues removed from ADA meeting

June 10, 2026
By Nuala Moran
No Comments
Former principal officers of the American Diabetes Association (ADA) have hit back at the association’s board and CEO after it prohibited the distribution of an editorial published in its flagship journal Diabetes Care at the ADA’s meeting in New Orleans last Friday.
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Liver anatomy on medical background
Gastrointestinal

Targeting TRIM54 mitigates liver injury in cirrhosis

June 10, 2026
No Comments
Researchers from Beijing University of Chinese Medicine described the role of TRIM54 in cirrhosis progression using two independent animal models of chronic liver injury – a DEN-induced rat model and a CCl4-induced mouse model of liver cirrhosis.
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RNA strand
Immune

TI-0032 induces B-cell depletion in preclinical setting

June 10, 2026
No Comments
Therorna Shanghai Co. Ltd. has presented data on TI-0032, an anti-CD19 CAR circular RNA therapeutic delivered by lipid nanoparticles (LNPs) for the treatment of autoimmune and hematological disorders.
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China compass

ASCO 2026: Chinese biopharma arrives at ASCO with pivotal wins

June 9, 2026
By Tamra Sami
No Comments
If the 2026 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from May 30 to June 3 demonstrated anything about the evolution of China’s biotechnology sector, it was that the industry’s center of gravity is shifting. While Chinese companies once relied heavily on PD-1 antibodies and licensing deals to gain international visibility, this year’s oral presentations showcased a broader innovation base.
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Dexcom G7 CGM

Pumps, patches and fixes at the ADA

June 9, 2026
By Shani Alexander
No Comments
Dexcom Inc. and Insulet Corp. reported new clinical trial data on their diabetes technologies at the 2026 Scientific Sessions of the American Diabetes Association in New Orleans, offering insights that could aid in clinical adoption. Abbott Laboratories, meanwhile, highlighted the risks of diabetic ketoacidosis (DKA) and presented data showing the growing challenge of identifying DKA as it can develop quickly and mimic common illnesses.
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Close-up of injector pen in hands

GLP-1s and more weigh in at ADA

June 9, 2026
By Brian Orelli
No Comments
GLP-1 receptor agonists remained center stage at the 2026 Scientific Sessions of the American Diabetes Association with Boehringer Ingelheim GmbH and Astrazeneca plc, joining the leaders, Eli Lilly and Co. and Novo Nordisk A/S, in presenting data for their respective GLP-1 drugs.
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Illustration of B cell releasing antibodies
Dermatologic

Kymera’s KT-579 shows promise for SLE treatment

June 9, 2026
No Comments
Kymera Therapeutics has developed KT-579, a potent and selective IRF5 degrader as a novel approach for treating systemic lupus erythematosus (SLE) and Sjögren disease.
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Illustration of pancreas, close up of islet
Endocrine/metabolic

CNTY-813 enables durable glucose control without immunosuppression need

June 9, 2026
No Comments
At the recent American Diabetes Association meeting, researchers from Century Therapeutics Inc. presented preclinical efficacy data on CNTY-813, an induced pluripotent stem cell (iPSC)-derived cell therapy engineered using the company’s proprietary Allo-Evasion 5.0 platform.
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Pancreatic cancer anatomy

Clinical footwork pays off in Tango’s PDAC combo phase I/II

June 8, 2026
By Randy Osborne
No Comments
Tango Therapeutics Inc. will be sitting down with the U.S. FDA soon to discuss pivotal work ahead based on what Cantor analyst Eric Schmidt called “amazing” data from the phase I/II study of vopimetostat, a PRMT5 inhibitor, paired with Revolution Medicines Inc.’s RAS(ON) inhibitors in patients with MTAP-deleted and RAS-mutant metastatic pancreatic ductal adenocarcinoma (PDAC) as well as non-small cell lung cancer.
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Liver anatomy illustration
Gastrointestinal

Dual ABCB4/ABCB11 modulation shows promise in cholestatic disease models

June 8, 2026
No Comments
Researchers from Rectify Pharmaceuticals Inc. presented preclinical efficacy data on RTY-406, a novel dual-acting ABCB4/MDR3 and ABCB11/BSEP modulator, in animal models of primary sclerosing cholangitis.
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